MDS Podcast

In this episode, Dr. Mitra Afshari speaks with Dr. Jen Nagao about her latest work highlighting the automation of subthalamic deep brain stimulation (DBS) with Evoked Resonant Neural Activity (ERNA) in Parkinson’s disease. They discuss the potential benefits of ERNA over beta power in the operating room and future opportunities to explore this newer neurophysiological marker for DBS programming.

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Journal CME is available until June 30, 2027.

Dr. Todd Gross and Dr. Laxman Bahroo discuss with Dr. Sara Schaefer the real-world use of daxibotulinumtoxinA in patients with cervical dystonia following initial clinical trials and FDA approval.

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Dr. Asif Doja explores the diagnostic possibilities of behavioral arrests and loss of postural reflexes in a young boy, and details the diagnostic approach to such cases.


View the case videos:


KCNMA1-Related Episodes of Behavioral Arrest and Loss of Postural Reflexes


Cataplexy in Patients Harboring the KCNMA1 p.N999S Mutation

Ms. Nicole Duff spends time with Mrs. Cassandra Mulcahy and Prof. Stefan Mainka, both of whom are qualified music therapists. They discuss the benefits of music therapy in treating both motor and non-motor symptoms in persons with Parkinson's disease. Different forms of music therapy are discussed, along with the physiology behind them. Lastly, possible future directions of music therapy in the rehabilitation of persons with Parkinson's disease were explored.

Dr. Sarah Camargos is joined by Dr. Rajeev Kumar to explore early research on targeting neuroinflammation in Huntington's disease. Dr. Kumar delves into the intricacies of the complement cascade, highlighting the pivotal role of C1q as the recognition molecule at the top of this immune system chain reaction and how ANX005 aims to prevent the initiation of the cascade. He further discusses the implications of biomarker advancements and safety protocols in moving towards more effective treatments for Huntington's disease.

Read the article.

Journal CME is available until June 30, 2027.