Gavin, Richard, and Jessamy enter the studio once more for a Lancet Voice chat. A new book on Alzheimer's disease causes controversy across the Lancet team, we discuss the new Countdown on Plastics & Health, and a quick look at the problems facing the upcoming UN High Level Meeting on NCDs.You can read the Lancet Countdown on health and plastics here:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01447-3/fulltext?dgcid=buzzsprout_tlv_podcast_August_25_lancetSend us your feedback!Read all of our content at https://www.thelancet.com/?dgcid=buzzsprout_tlv_podcast_generic_lancetCheck out all the podcasts from The Lancet Group:https://www.thelancet.com/multimedia/podcasts?dgcid=buzzsprout_tlv_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
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Step counts and health outcomes - 7,000 or 10,000?
Where did the 10,000 steps recommendation come from? Why has it proven so stubborn? What's the science behind the new recommendations? How strong is the evidence?Professor Melody Ding joins Gavin to talk about her new systematic review published in The Lancet Public Health, examining the relationship between step counts and health outcomes. We also explore the challenges of measuring physical activity, the importance of inclusive research, and the role of environmental and policy interventions in promoting population health.Read the article from The Lancet Public Health here:https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00164-1/fulltext?dgcid=buzzsprout_tlv_podcast_August_25_lanpubSend us your feedback!Read all of our content at https://www.thelancet.com/?dgcid=buzzsprout_tlv_podcast_generic_lancetCheck out all the podcasts from The Lancet Group:https://www.thelancet.com/multimedia/podcasts?dgcid=buzzsprout_tlv_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
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27:24
The next generation of weight-loss drugs
It’s no exaggeration to say that the past decade has revolutionized how we think about and treat obesity. Drugs like semaglutide (Wegovy) and tirzepatide (Zepbound) have dominated headlines, enabling significant weight loss at speeds once considered unthinkable. The market for innovative weight loss medications is booming, with pharmaceutical companies investing heavily in hopes of developing the next blockbuster drug.However, amid this race for market dominance, many experts are questioning whether the amount of weight loss alone is the best measure of these drugs’ usefulness. How can the next generation of obesity treatments meaningfully improve upon the powerful options already available?Joining The Lancet editors Callam Davidson and Miriam Sabin to discuss this question is Professor Steven Heymsfield from the Pennington Biomedical Research Center. This wide-ranging conversation covers exciting pharmaceutical advances and limitations of these treatments, including the significant disparities in access, and why these breakthroughs may have broader societal implications.Send us your feedback!Read all of our content at https://www.thelancet.com/?dgcid=buzzsprout_tlv_podcast_generic_lancetCheck out all the podcasts from The Lancet Group:https://www.thelancet.com/multimedia/podcasts?dgcid=buzzsprout_tlv_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
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38:11
Proof, truth, and infectious disease
Professor Adam Kucharski joins Gavin & Jessamy to discuss the intersection of mathematics, epidemiology, and truth, off the back of his new book, Proof. How do we generate scientific knowledge? How can we communicate uncertainty? What is the impact of social media and artificial intelligence on public trust in science?Adam also tells us about the importance of public engagement, the nuances of misinformation, the importance of transparency in policy, the future of scientific communications, the need for adaptable definitions of proof, and the value of pragmatic, transparent approaches to decision-making in health and science.Send us your feedback!Read all of our content at https://www.thelancet.com/?dgcid=buzzsprout_tlv_podcast_generic_lancetCheck out all the podcasts from The Lancet Group:https://www.thelancet.com/multimedia/podcasts?dgcid=buzzsprout_tlv_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
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38:23
Femtech and women's health
How safe is it to use period tracking and digital contraception apps? Who is your data being shared with? What regulation actually exists in this area to protect app users?Femtech offers women digital tools for tracking reproductive health. Gavin and Jessamy are joined by Dr. Catriona McMillan, Senior Research Fellow in Medical Law and Ethics at the University of Edinburgh, to talk about how accurate these apps actually are, significant concerns about data privacy, and what regulatory oversight exists and can be applied.Send us your feedback!Read all of our content at https://www.thelancet.com/?dgcid=buzzsprout_tlv_podcast_generic_lancetCheck out all the podcasts from The Lancet Group:https://www.thelancet.com/multimedia/podcasts?dgcid=buzzsprout_tlv_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
The Lancet Voice is a fortnightly podcast from the Lancet family of journals. Lancet editors and their guests unravel the stories behind the best global health, policy and clinical research of the day―and what it means for people around the world.