The Lancet Voice

Those working in clinical trials will recall that in 2025 updates were published for the SPIRIT standard clinical trial protocol items and the CONSORT guideline for reporting randomised clinical trials. The Lancet Child & Adolescent Health will be co-publishing the first child and adolescent extensions to the SPIRIT and CONSORT reporting guidelines, along with the BMJ and JAMA Paediatrics. In this conversation with the SPIRIT and CONSORT child and adolescent project leads, Ami Baba and Martin Offringa, we discuss the need for child and adolescent specific reporting standards, the importance and value of engaging caregivers and young people in the process of developing the standards, and the potential for the SPIRIT-C and CONSORT-C reporting standards to positively impact the quality and inclusivity of paediatric clinical trials across all disciplines caring for neonates, infants, children, and adolescents.
Click here to read the full articles:
CONSORT-C https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(26)00004-0/fulltext
SPIRIT-C https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(26)00005-2/fulltext
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In this episode Jessamy talks to Iris Blom, a medical doctor and researcher with the London School of Hygiene & Tropical Medicine and co-chair on The Lancet Commission on Sustainable Healthcare.
Iris details her role at the recent COP30 in the Brazil Amazon, translating research for negotiators and advancing evaluation frameworks for sustainable healthcare, tells her takeaways from the conference and also explains why multilateralism still matters, how city-led co-benefits can drive measurable action, and what to expect from the upcoming Just Transition away from fossil fuels conference that  will take place on 28-29 April 2026 in Santa-Marta, Colombia.
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Jessamy is joined by Chloe to co-host as they meet with Dr Mumtaz Patel President of RCP and Consultant nephrologist.

Dr. Patel discusses ongoing challenges for Resident Doctors and reflects on the changes that are needed to improve the current training pathways in the UK.

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Gavin is joined by Dr. Seth Berkley, former CEO of Gavi, the Vaccine Alliance, to discuss his new book, Fair Doses.

Dr. Berkley reflects on the global impact of vaccines, the ongoing challenges to vaccine equity, and the lessons learned from leading initiatives such as COVAX during the COVID-19 pandemic.

We also discuss the economics of vaccine distribution, the threat of misinformation, the promise of scientific innovation, and the future of global health preparedness, and a vision for strengthening international cooperation and ensuring that future advances in vaccine science benefit everyone, everywhere.
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Gavin is joined once again by Richard and Jessamy as they examine key developments in global health and science.

This week's discussion features reflections on the launch of a new Lancet series on Alzheimer’s disease, highlighting advances in prevention, diagnosis, and care, as well as the ethical and practical challenges posed by emerging treatments.

We also explore the global landscape of liver cancer, demographic change, the shifting centre of scientific research, and recent studies on human longevity. Join us for a thoughtful, evidence-based conversation on pressing issues in health, policy, and research worldwide.
Read the full series: https://www.thelancet.com/series-do/alzheimers-disease
Read the full commission: https://www.thelancet.com/commissions-do/hepatocellular-carcinoma
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Read all of our content at https://www.thelancet.com/?dgcid=buzzsprout_tlv_podcast_generic_lancet

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