FRESH-UP Study: Liberal Fluid Intake Versus Fluid Restriction in Chronic Heart Failure
Fluid restriction is often recommended for heart failure (HF) patients to prevent congestion, but its benefits and safety are unclear. The FRESH-UP study is the first to show that strict fluid restriction does not improve health status for chronic, symptomatic HF patients and may increase thirst distress without reducing mortality, hospitalization, acute kidney injury, or medication needs. In this interview, Roland RJ van Kimmenade, MD and Alison L. Bailey, MD, FACC discuss the impacts of the FRESH-UP study and how liberal fluid intake is safe for chronic HF patients, even enhancing their well-being. Providers are encouraged to reconsider universal fluid restrictions and adopt a more individualized approach. RELATED REFERENCES: Herrmann JJ, Brunner-La Rocca HP, Baltussen LE, et al. Liberal Fluid Intake Versus Fluid Restriction in Chronic Heart Failure: A Randomized Clinical Trial. Nat Med 2025;Mar 30:[Epub ahead of print].
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Chronic Thromboembolic Pulmonary Hypertension (CTEPH): Procedures or Pills?
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and potentially fatal form of elevated blood pressure in the lungs. CTEPH treatment overall is a very complex clinical assessment and medical decision. Treatment options may include pulmonary thromboendarterectomy (PTE) surgery, balloon pulmonary angioplasty (BPA), or medical therapy. In this interview, Drs. Shashank Sinha and Anjali Vaidya discuss how to approach the treatment decision for CTEPH once a diagnosis has been made. Subscribe on Apple Podcasts | Subscribe to ACCEL
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A Look at The 2024 AHA/ACC Perioperative Guideline s
The 2024 American Heart Association/American College of Cardiology (AHA/ACC)/multisociety guideline for perioperative cardiovascular (CV) management for noncardiac surgery, released in September 2024, marks the fourth comprehensive revision of the perioperative guideline since its inception in 1996. This latest update reflects the most current, evidence-based recommendations, shaped by expert clinical insight, to guide the management of patients with CV conditions undergoing noncardiac surgery. In this interview, Drs. Andrew Kates and Annemarie Thompson discuss the key updates from the 2014 guideline, highlighting significant changes and exploring its guidance on evaluating patients with CV disease before noncardiac surgery. Subscribe on Apple Podcasts | Subscribe to ACCEL
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The Evolving Therapeutic Landscape in Obesity and the Effect on CV Outcomes
In this interview, Drs. Richard Chazal and Mikhail Kosiborod explore the rapidly evolving therapeutic landscape of obesity, with a particular focus on the cardiovascular benefits of emerging treatments. They delve into the impact of sodium-glucose co-transporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists in enhancing cardiovascular outcomes and improving survival across diverse clinical settings. Their discussion highlights the latest advancements in these therapies, shedding light on their role in reshaping the management of cardiometabolic diseases. Subscribe on Apple Podcasts | Subscribe to ACCEL
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Getting the Most Out of ChatGPT and Other Large Language Models in Cardiology
Drafting messages, summarizing charts, managing appointments, and assessing eligibility are all tasks that large language models can streamline. However, integrating them safely and effectively—whether in small practices or large healthcare institutions—poses unique challenges. In this interview, Drs. Dipti Itchhaporia and Marly van Assen explore key strategies and safeguards designed to reduce errors and enhance reliability in high-stakes environments like healthcare. Subscribe on Apple Podcasts | Subscribe on Google Play | Subscribe to ACCEL
Sobre ACCEL Lite: Featured ACCEL Interviews on Exciting CV Research
The American College of Cardiology offers select interviews and summaries of cardiology’s most interesting research areas from ACCEL’s renowned library, hosted by ACCEL Editor-in-Chief Alison L. Bailey, MD, FACC, FAACPVR.
Ouça ACCEL Lite: Featured ACCEL Interviews on Exciting CV Research, Psicanálise de Boteco e muitos outros podcasts de todo o mundo com o aplicativo o radio.net