This Week in AI

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Today’s show:
The price of tokens keeps tumbling down, and it’s changing who controls AI.

Grok 4.5 and GLM-5.2 landed within two weeks of one another, offering powerful alternatives at a fraction of frontier prices. But are SpaceXAI’s latest offering and open weight models truly ready to replace Opus, GPT-5.5, and Fable? Are enterprises finally ready to stop renting and start owning their intelligence?

On TWiAI Episode 22, Jason and Lon welcome three top founders — Sara Hooker (Adaption Labs), Manu Sharma (Labelbox), and Spiros Xanthos (Resolve AI) — to break down the global AI price war, and what it means for the frontier labs and customers alike. Plus Denis Hassabis’ call for an AI Standards Body, Uber and Waymo duke it out over DC robotaxis, and is SpaceXAI really going to put data centers in orbit any time soon?

Guests:

Sara Hooker on X: https://x.com/sarahookr
Adaption Labs: https://adaptionlabs.ai/
Manu Sharma on X: https://x.com/manuaero
Labelbox: https://labelbox.com/
Spiros Xanthos on X: https://x.com/spirosx
Resolve AI: https://resolve.ai/
Relevant Links
Introducing Grok 4.5**:** https://x.ai/news/grok-4-5
GLM from Z.ai: https://z.ai
Artificial Analysis Intelligence Index: https://artificialanalysis.ai/
Demis Hassabis: “A Framework for Frontier AI and the Dawning of a New Age”: https://x.com/demishassabis/status/2076957440109625718
Cerebras: https://www.cerebras.ai/
Austin Allred post cited by Jason: https://x.com/Austen/status/2076745226387902925
TechCrunch coverage of DC autonomous driving bill: https://techcrunch.com/2026/07/13/ubers-robotaxi-lobbying-effort-has-put-it-on-a-collision-course-with-waymo/
DoorDash: Meet Dot: https://about.doordash.com/en-us/dot
TechCrunch coverage of orbital data center debate: https://techcrunch.com/2026/07/13/sam-altmans-space-data-center-trash-talk-is-what-most-experts-already-believe
Falcon 9 booster’s record 36th flight: https://spaceflightnow.com/2026/07/09/live-coverage-spacex-to-launch-falcon-9-rocket-on-record-breaking-36th-flight/
Timestamps:0:00 A new generation of lower-cost models
4:10 Enterprises want their own intelligence stack
6:10 Frontier vs. open source: where does the value go?
10:03 Is enterprises destined to go small?
30:04 Self-improvement as the real fix
31:52 Should the AI industry regulate itself?
47:14 Uber vs. Waymo in DC
1:03:53 Can AI data centers in space really work?
1:14:47 You get a plug! Everyone gets a plug!
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Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
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Today’s show:

China is weighing a ban on foreign access to its top AI models… the same low-cost open-weight systems on which half of the Valley’s startups are building. So we asked our two all-star panelists — Arena CEO/Co-Founder Anastasios Angelopoulos and Hippocratic AI CEO/Co-Founder Munjal Shah — what happens to US companies when their favorite cheap, powerful models vaporize overnight.
PLUS why Hippocratic runs 31 models in parallel to ensure clinical-grade safety, the latency-vs-intelligence tradeoff no one is optimizing for, and why a company’s benchmarks might become their most valuable IP.

Guests:

Anastasios Angelopoulos on X: https://x.com/ml_angelopoulos
Arena AI: https://arena.ai/
Agent Arena: https://arena.ai/leaderboard/agent
Munjal Shah on X: https://x.com/munjalshah
Hippocratic AI: https://hippocraticai.com/

Relevant Links:

Reuters: “Beijing is looking at curbing overseas access…”: https://www.reuters.com/world/beijing-is-looking-curbing-overseas-access-chinas-top-ai-models-sources-say-2026-07-07/
Z.ai: https://z.ai/
Alibaba’s Qwen: https://qwen.ai/
Google’s Gemma: https://ai.google.dev/gemma
Reflection AI: https://reflection.ai/
Nvidia: “How Open Models are Driving Research”: https://blogs.nvidia.com/blog/open-models-icml-2026/
DoorDash: “How we learned to trust our AI code reviewer”: https://careersatdoordash.com/blog/how-we-learned-to-trust-our-ai-code-reviewer-at-doordash
Harvey AI: https://www.harvey.ai/
ElevenLabs: https://elevenlabs.io/
Anthropic: “A global workspace in language models”: https://www.anthropic.com/research/global-workspace
CNN: “Trump rings opening bell to mark first day of trading for Trump Accounts”: https://www.cnn.com/2026/07/06/business/trump-accounts-launch
Brown University Health: https://www.brownhealth.org/

Timestamps:

0:00 Will US companies lose access to Chinese models?
1:42 Open source makes running 31 models viable
5:01 How deep is the West's open source bench?
13:20 Jagged Intelligence and why post-training matters
25:22 Benchmarks as living quality checks
32:49 Why models still struggle with drug names
42:58 Fine-tuning TV, cough, and sob detection
46:08 What is Arena actually selling?
1:08:29 Nationalization vs. buying stakes in AI companies
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LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm
Follow Jason:
X: https://twitter.com/Jason
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
Check out all our partner offers: https://partners.launch.co/
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
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Today’s show:

The US government won’t let you use the most powerful releases from US AI labs… but a Chinese lab is giving away their latest frontier model for free.
This week, we’ve got three AI CEOs building in image generation (Victor Perez of Krea), mobile agents (Div Garg of The AGI Company), and enterprise governance (Andrew Berman of Runlayer). Together, they’re breaking down what’s really happening underneath all this chaos, and why the industry’s more focused on “minimum viable intelligence” over breaking benchmarks.
Guests
Victor Perez on X: https://x.com/viccpoes
Krea AI: https://www.krea.ai/
Krea 2 Raw and Turbo on Hugging Face: https://huggingface.co/krea/Krea-2-Raw
Div Garg on X: https://x.com/divgarg
The AGI Company: https://theagi.company/
Andrew Berman on X: https://x.com/berman66
Runlayer: https://www.runlayer.com/
Relevant Links
Anthropic: “Introducing Claude Sonnet 5”: https://www.anthropic.com/news/claude-sonnet-5
Z.ai: GLM-5.2: https://docs.z.ai/guides/llm/glm-5.2
Yuchen Jin X post: “GLM-5.2 is the open source Claude moment”: https://x.com/Yuchenj_UW/status/2071278256817574297
TechCrunch: GPT-5.6 restricted rollout coverage: https://techcrunch.com/2026/06/26/openai-limits-gpt-5-6-rollout-after-government-request-says-restrictions-shouldnt-be-the-norm/
AndroidWorld benchmark on GitHub: https://github.com/google-research/android_world
The Information Higgsfield valuation article: https://www.theinformation.com/articles/ai-video-startup-talks-quadruple-valuation-5-billion
Agentic AI Foundation (AAIF): https://aaif.io/
Tomasz Tunguz: “When AI Costs More Than The Engineer”: https://tomtunguz.com/ai-spend-breakeven-2029/
Fortune Runlayer raise coverage: https://fortune.com/2026/06/24/exclusive-vinod-khosla-felicis-runlayer-nanit-30-million-enterprise-ai/
Gusto: https://gusto.com/
Timestamps:
0:00 Making sense of US AI policy
5:09 Tiny Action Models vs. LLMs
7:02 Runlayer, AGI Inc, and computer-use agents
10:05 What does "trusted access" really mean?
12:37 Why Krea open sourced its image model
22:21 BREAKING: Claude Sonnet 5 is here
26:00 GLM-5.2 is the open source Claude moment
31:58 Personalization and corporate ontology
41:25 Can we trust Higgsfield's numbers?
50:39 Distillation: The threat is real
58:01 Agentic personhood and corporate rights
1:03:19 Everyone's AGI timeline and p(doom) score
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Follow Lon:
X: https://x.com/lons
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X: https://x.com/alex
LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm
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X: https://twitter.com/Jason
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
Thank you to our partners:

Check out all our partner offers: https://partners.launch.co/
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
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Today’s show:
*When we think of “Physical AI,” most of us conjure images of humanoid robots and self-driving cars. But there’s a lot more to the category than just breakdancing Chinese bots and Waymos, from excavators autonomously digging tomorrows worksites, to a robot the size of four pizza boxes deploying to the ISS.
Guest host Alex Wilhelm sits down with three founders in the trenches of the Physical AI Space:
Boris Sofman of Bedrock Robotics, which builds autonomous construction equipment
Jeff Hawke of Odyssey, a frontier AI lab specializing in world models for robotics and video games
Ethan Barajas of Icarus Robotics, designers of the free-flying Joy robot that will join the ISS crew in 2027
Guests:
Boris Sofman on X: https://x.com/bsofman
Bedrock Robotics: https://bedrockrobotics.com/
Jeff Hawke on X: https://x.com/jeffrey_hawke
Odyssey: https://odyssey.ml/
Ethan Barajas on X: https://x.com/ethanbarajas11
Icarus Robotics: https://www.icarusrobotics.com/
Relevant Links
Bedrock Excavators Remove 65,000 Cubic Yards of Dirt: https://www.enr.com/articles/61982-bedrock-robotics-excavators-remove-65-000-cubic-yards-of-dirt-on-southwest-project
Odyssey $310M Series B article: https://techcrunch.com/2026/06/17/world-model-maker-odyssey-nabs-1-45b-valuation-backed-by-amazon-and-other-big-names/
Icarus “Joyride” Mission announcement: https://thedebrief.org/icarus-is-building-the-robotic-labor-force-for-space-voyager-technologies-is-sending-a-next-generation-zero-gravity-robot-on-a-joyride-to-space/
PROWL: Prioritized Regret-Driven Optimization for World Model Learning: https://arxiv.org/abs/2605.18803
NVIDIA Cosmos 3 report: https://research.nvidia.com/labs/cosmos-lab/cosmos3/technical-report.pdf
ISS Columbus Laboratory Module: https://www.nasa.gov/international-space-station/columbus-laboratory-module/
NASA’s Astrobee flying robot: https://www.nasa.gov/astrobee/
Voyager Technologies: https://www.voyagerspace.com/
Vast Space: https://www.vastspace.com/
Blue Origin’s New Glenn: https://www.blueorigin.com/new-glenn
“Red Mars” by Kim Stanley Robinson: https://www.amazon.com/Red-Mars-Stanley-Robinson/dp/0553560735
“Rendezvous with Rama” by Arthur C. Clarke: https://www.amazon.com/Rendezvous-Rama-Arthur-Clarke/dp/0553287893
Theo Von “This Past Weekend” podcast: https://www.theovon.com/podcast
Anthropic statement on Fable/Mythos suspension: https://www.anthropic.com/news/fable-mythos-access
Timestamps:
0:00 The Year of Physical AI
1:28 Why everyone's bullish on world models
7:03 Physical AI is harder, but probably bigger
9:08 How to think about world models
16:00 When data becomes "adversarial"
25:00 How Bedrock powers autonomous excavators
30:48 Why teleoperation gets a bad rap
39:10 Meet Joy the space robot
41:33 Laser comms coming to next-gen stations
46:29 Why everyone hates data centers
57:33 When does Claude Fable come back?
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X: https://x.com/lons
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LinkedIn: https://www.linkedin.com/in/jasoncalacanis
Check out all our partner offers: https://partners.launch.co/
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
Check out Jason’s suite of newsletters: https://substack.com/@calacanis
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SpaceX bought Cursor for $60 billion. Satya Nadella says companies need to stop relying on third party AI models and build their own “token capital.” The focus is shifting from LLMs to the application layer sitting on top of them. Here to unpack what that means are guest experts Ali Ansari (Micro1) and Ryan Daniels (Crosby).Plus we get a sneak peek at their new contract redlining benchmark, a crucial eval for how well LLMs don’t just answer questions about the law, but demonstrate actual legal reasoning.Timestamps:0:00 SpaceX acquires Cursor7:36 Distillation vs. building your own model19:43 Nadella's "Frontier Without an Ecosystem"30:21 AI in the courtroom32:15 Ando: the intriguing new workplace tool1:05:38 Inside Micro1 and Crosby's new benchmark1:07:14Guests:Ali Ansari: https://x.com/aliansarinikMicro1: https://www.micro1.ai/Ryan Daniels: https://x.com/ryanjdanielsCrosby: https://crosby.ai/Relevant Links:Bloomberg: “SpaceX acquires Cursor for $60B”: https://www.bloomberg.com/news/articles/2026-06-16/spacex-cements-60-billion-deal-to-take-over-ai-startup-cursorQuinn Thompson “brilliant corporate finance” post: https://x.com/qthomp/status/2066859672749977988Business Insider: “Inside Cursor’s Wild Rise”: https://www.businessinsider.com/cursor-ceo-michael-truell-spacex-elon-musk-anthropic-2026-6Satya Nadella: “A frontier without an ecosystem is not stable”: https://x.com/satyanadella/article/2066182223213293753Joshua Browder’s Do Not Pay: https://donotpay.com/Harvard Magazine: “AI Outperforms Doctors in Emergency Room Tasks”: https://www.harvardmagazine.com/ai/ai-outperforms-doctors-diagnosis-harvard-studyJoshua Kushner “Long Humans” post: https://x.com/JoshuaKushner/status/2065093542809092465Ando: https://ando.so/Nim Ravid on X: https://x.com/Nim_Ravid1Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com