Advancements and Challenges in GLP-1 Peptide Drugs
This episode of Chromatography Life takes a closer look at the evolving landscape of synthetic peptide drugs - one of the most compelling frontiers in biopharmaceutical analysis. Joining us is Matt Lauber, Senior Director at Waters and a recognized authority in bioanalysis and drug product characterization, who shares both his personal and professional journey, along with his insights into the science shaping today’s peptide therapeutics. We discuss the growing significance of GLP-1 peptide drugs, the analytical hurdles they present, and the chromatographic techniques that help ensure their safety and effectiveness. Whether you're already immersed in the world of drug development or just peptide-curious, this conversation provides the right dose of thoughtful perspective on how innovation and precision change are changing the future of human health.
--------
23:58
Challenges of Chromatographic Analysis for New Modalities
Join host Neil Lander on Chromatography Life as he interviews, Arnaud Delobel, R&D and Innovation Director at Quality Assistance. In this episode, Arnaud discusses chromatographic analysis for new modalities, with adeno-associated viruses (AAVs) in the spotlight. He discusses the complexities of analyzing these large biomolecules and the innovative techniques being developed to improve their characterization. Tune in to glimpse the future of chromatography and learn about the incredible advancements that are helping to tackle some of the toughest human health challenges.
--------
27:59
Automating Dissolution in the Laboratory
Join host Neil Lander on Chromatography Life as he interviews Ben Calvopina, Application Scientist and expert in dissolution testing at SOTAX. Ben shares his journey from service engineering to leading automation projects, highlighting the impact of automation on efficiency and accuracy in pharmaceutical quality control. The episode explores the practical aspects of automating dissolution methods and the importance of validation to ensure reliable results. Tune in to this episode to learn about the latest trends and future directions in chromatography and dissolution.
--------
14:15
The Evolution of UPLC Columns
In this episode of the Chromatography Life podcast, our host Neil Lander sits down with Tom Walter, a corporate fellow at Waters, to explore the fascinating journey of UPLC column evolution. Tom, a seasoned expert with numerous patents and innovations under his belt, shares his experiences and insights from his extensive career in chromatography. From the early days of large particle columns to the cutting-edge small particle technology of today, Tom discusses the challenges, breakthroughs, and environmental impacts of UPLC advancements. Join us for an engaging conversation that sheds light on the past, present, and future of chromatography with one of the field's most respected leaders.
--------
14:22
Validating Chromatographic Methods: Challenges, Tools, and Optimization
Join host Neil Lander as he welcomes Katy Rhynard, Associate Director of Laboratory Informatics at Gilead Sciences. In this episode, Katy discusses the intricacies of validating chromatographic methods, including guidelines and regulatory requirements, key success metrics, documentation, techniques, and tools. Katy details the pervasive challenges in method validation, and how to effectively leverage tools in Empower to optimize stages throughout the process. Katy guides us through the steps to upgrade our lab’s method validation processes and shares how Empower’s Method Validation Manager supports lab teams in their calculations and compliance, so they can truly ‘focus on the chromatography’.
Welcome to Chromatography Life, a podcast presented by Waters Corporation. Join us as we dive into the world of chromatography with leading scientists to examine today’s critical challenges. As a hub for the chromatography community, we share the lived experiences, passions, and visions of these scientific innovators as they shape the future of analytical chemistry.
Hear from experts across a wide range of topics, spanning chromatographic methods, laboratory solutions, column chemistry, and software innovations. Explore problem-solving strategies across issue areas including patient safety, food safety, environmental issues like PFAS, and ways to enhance global wellbeing. We’ll also delve into the complexities of regulatory compliance, data integrity, and the evolving landscape of scientific research.
We’re excited for you to join the community of chromatography experts and enthusiasts. Share your thoughts and the topics you’re passionate about; we look forward to hearing from you!
Brasil