Daily Value

• Magnesium: The ‘Best’ Form Isn’t What You Think Part 1.

  Magnesium supplements are marketed like different compounds with different biological targets - i.e., “for sleep,” “for the brain,” “for stress,” “for energy.” But the foundation of these claims depends on chemistry: how magnesium salts dissolve, how they release Mg²⁺ in the gut, and how much actually reaches circulation.Part 1 breaks down the first half of the magnesium story: why magnesium must be paired with a counter-ion, how dissolution determines real absorption, and what modern data show when common salts like citrate, glycinate, and oxide are compared head-to-head.The goal: separating marketing myths from measurable differences in solubility, acute bioavailability, and baseline magnesium status00:00 Introduction to Magnesium Forms00:30 Magnesium's Chemical Nature01:11 Absorption Differences Among Magnesium Forms01:35 Clinical Studies on Magnesium Absorption04:24 Magnesium in Animal Studies06:05 Human Studies on Magnesium08:47 Conclusion and Preview of Part TwoDoi: 10.1186/s40795-016-0121-3PMID: 11550076PMID: 31330811PMID: 39252819PMID: 26519439PMID: 34111673PMID: 23853635doi: 10.3390/nu9050429PMID: 39009081

  --------  

  9:25

  --------

  9:25
• Common Longevity Medication… Performance Killer?

  A medication used by millions (including off-label usage for “longevity” purposes) may alter the fundamental pathways responsible for exercise adaptation. This episode reviews new 2025 data showing reduced improvements in vascular insulin sensitivity, aerobic capacity, and glucose regulation when the medication is paired with structured training. We look at prior evidence of blunted mitochondrial respiration and diminished hypertrophy, along with 2020 transcriptomic findings that paint a more nuanced picture.The goal: clarify when this medication interferes with exercise-driven improvements in muscle, mitochondria, and vascular function, and when it may support resilience during aging.00:00 – Intro00:48 – The Rise of a “Longevity” Medication01:31 – New Clinical Data Challenges Expectations03:34 – Earlier Trials Showed the Same Pattern05:05 – Resolving the Apparent Contradiction07:10 – Who Should, and Shouldn’t, Use This MedicationPMID: 30548390PMID: 31557380PMID: 33071237PMID: 37928155

  --------  

  8:29

  --------

  8:29
• The Mitochondrial “Vitamin” from Interstellar Dust

  There’s a molecule that’s been tentatively identified in the same interstellar material that forms stars and planets, yet it also shapes growth, metabolism, and cognition here on Earth. In several mammalian species,Its absence causes deficiency and it's repletion, resolution; and no, it’s not a vitamin, but should it be?Its chemistry is analogous to the combination of vitamin B2, vitamin B6 vitamin C, and its role in evolution may trace back to the very beginning of biology.00:00 – From Interstellar Dust to Human Biology01:06 – Discovery: A New Redox Co-Factor01:44 – Biological Role: Deficiency, Growth, and Evolution02:41 – Mechanisms: NAD⁺ Regeneration and Mitochondrial Signaling03:11 – Human Evidence: Cognitive and Metabolic Effects04:41 – Chemistry & Safety: Potency and Tolerability06:55 – Conclusionhttps://pmc.ncbi.nlm.nih.gov/articles/PMC8533503/

  --------  

  7:50

  --------

  7:50
• Boost Your Serotonin Naturally: The Nutrition Secret

  Serotonin is often described as the “happiness molecule,” but its biology tells a larger story. Nearly every step in serotonin’s synthesis and signaling, from the transport of dietary tryptophan to the enzymes that convert it, is influenced by nutrition.This episode examines how macronutrients, micronutrients, and gut-derived metabolites shape serotonin availability across the brain and body. Protein and carbohydrate balance determine how much tryptophan enters the brain. Specific vitamins and minerals serve as essential cofactors in its production and turnover, and so on…Understanding serotonin through this nutritional lens reframes it not as a simple neurotransmitter, but as a metabolic signal connecting diet, metabolism, and mood regulation.00:00 Introduction to Serotonin01:07 Evolutionary Role of Serotonin02:08 Nutritional Influence on Serotonin Synthesis02:55 Enzymatic Pathways of Serotonin Production04:21 Macronutrients: Impact on Serotonin06:32 Vitamins and Minerals: Impact on Serotonin09:27 Plant Compounds and Gut Microbiome: Impact on Serotonin10:24 Serotonin as a Biochemical Bridgehttps://pubmed.ncbi.nlm.nih.gov/40998119/

  --------  

  11:25

  --------

  11:25
• Discovered: an amino acid that helps the gut heal itself

  Every few days, your gut rebuilds itself completely - cell by cell, guided by signals we still don’t fully understand. For years, scientists have known that diet can influence this process, but the exact messenger between what we eat and how the gut heals has remained a mystery.In this episode, we look at new research from MIT that uncovers a surprising link between diet, the immune system, and regeneration in the intestine. It’s a story about how a single nutrient can activate immune cells to release molecules that tell the gut when it’s time to repair.It challenges the way we think about food, not just as fuel, but as information. Because the gut isn’t just digesting what we eat… it’s listening.00:00 Introduction to Gut Regeneration00:56 The Role of Amino Acids in Gut Health02:07 ???: A Key Player in Gut Regeneration02:35 MIT's Groundbreaking Research 03:49 The Immune System's Role in Gut Regeneration05:51 Dietary Sources and Implications 07:07 Conclusion: The Gut's Adaptive NaturePMID: 41034585

  --------  

  7:42

  --------

  7:42

Mais podcasts de Saúde e fitness

Podcasts em tendência em Saúde e fitness

Sobre Daily Value