Discover CircRes

This month on Episode 88 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the August 28th and September 11th issues of Circulation Research. This Episode also features a discussion with Dr Klaus Ley about his study, "Increased Autoreactive CD8+ T Cells to Apolipoprotein B Epitopes in Patients with Severe Coronary Artery Disease."
 
Article highlights:
Wang, et al. Methylmalonate Drives Diabetic Heart Damage
Zheng, et al. TLS and CXCL13 Axis in Intracranial Aneurysms
Zhou, et al. A Glyco-Epigenetic Driver of Heart Failure
Wang, et al Formononetin as an ERRα Agonist Alleviates AIC

This month on Episode 87 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the July 31st and August 14th issues of Circulation Research. This Episode also features a discussion with Drs Jonathan Kirk, Laura Sherer, and Abigail Nagle about their study, "Contractility Drives Cardiomyocyte Maturation and the Response to Nanopatterns."
 
Article highlights:
Zhang, et al. Mitochondrial STING Reprograms Glycolysis
Daou, et al. TFEB Antagonizes Pathological Cardiac Hypertrophy
Crepin, et al. Macrophage Subsets Contribute to Atrial Remodeling
Okamura, et al. Stochastic Resonance Prevents Sinus Arrest

This month on Episode 86 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the July 6 and July 17th issues of Circulation Research. This Episode also features a discussion with BCVS Outstanding Early Career Investigator Award Finalists, Drs Noor Momin, Shibali Das, and Ivan Menendez-Montes.
 
Article highlights:
Kotla, et al. LATS1/2-CD38-SUOX Axis Drives Intraplaque Thrombosis
Lin, et al. ATAD3A Gates Mito-Lysosome Contacts in AAD
Wang, et al. Monocyte Dll4 Induces Systemic Inflammation
Chattopadhyay, et al. S100A8/A9 Aggravate Atherosclerosis

This month on Episode 85 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the May 22nd, June 5th and June 19th issues of Circulation Research. This Episode also features a discussion with Professor Katrin Schäfer, Dr Rajinikanth Gogiraju, and Dr Beichen Sun, about their study, Chronic Erythrocyte NO Production Accelerates Atherosclerosis by Increasing SMC De Novo Lipogenesis.
 
Article highlights:
Larcher, et al. Cardiac Fibroblast Heterogeneity and Disease
Huang, et al. Vascular Endothelial NOX1 Drives Obesity
Atici, et al. Role of Sirtuin-1 in Murine Vasculitis
Compendium on Lipoproteins and Cardiovascular Disease

This month on Episode 84 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the April 24th and May 8th issue of Circulation Research. This Episode also features a discussion with Dr Mete Civelek and Dr Noah Perry about their study, Female-Biased Vascular Smooth Muscle Cell Gene Regulatory Networks Predict MYH9 as a Key Regulator of Fibrous Plaque Phenotype.
 
Article highlights:
Westhoff, et al. PTEN and PIP3 in AngII-Induced Cardiac Pathology
Witmer, et al. Novel Mode of SCN5A-Mitochondrial Crosstalk
Ghiringhelli, et al. Light-Controllable Humanized Bioengineered Atria
Wang, et al. Exercise-Induced Cardiomyocyte EVs Deliver EPPIR