Each 15-minute podcast will provide an overview of the issue’s contents and relevant news in the field of basic/translational cardiovascular biology followed by...
This month on Episode 68 of Discover CircRes, host Cindy St. Hilaire highlights four articles featured in the January 3rd and January 17th issues of Circulation Research. This Episode also includes a discussion with Drs Gianluigi Condorelli and Marinos Kallikourdis about their study Autoimmune-like Mechanism in Heart Failure Enables Preventative Vaccine Therapy. Article highlights: Yoshida, et al. FAP Vaccine Improves Cardiac Fibrosis Johansen, et al. TCF21 and Cardiac Fibrosis Pabon, et al. Endothelial METAP1 in Preeclampsia Mutchler, et al. ET-3/ETBR, Immune Cells, and Kidney Lymphatics
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34:19
Discover CircRes December 2024
This month on Episode 67 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the December 6th issues of Circulation Research. This Episode also includes a discussion with Drs Jesse Rowley and Shancy Jacob about their study, Mitofusin-2 Regulates Platelet Mitochondria and Function. Article highlights: Bardhan, et al. Sex Specific Roles of Microbiota in Hypertension Ma, et al. Kindlin-2 LLPS Controls Vascular Stability Wang, et al. CAR-Ms Alleviate Myocardial I/R Injury
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26:05
Discover CircRes November 2024
This month on Episode 66 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the October 25th and November 8th issues of Circulation Research. This Episode also includes a discussion with Dr Jil Tardiff and Dr Melissa Lynn about their study, Arg92Leu-cTnT Alters the cTnC-cTnI Interface Disrupting PKA-Mediated Relaxation. Article highlights: Lou, et al. Visualizing irAEs in Atherosclerosis Yoshii, et al. Defective Mitophagy Response in HFpEF Heart Zeller, et al. Shear Stress Dissociates C-Reactive Protein Chen, et al. EPHB4-RASA1 Regulation of Lymphatic Valvulogenesis
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40:51
October 2024 Discover CircRes
This month on Episode 65 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the September 27th and October 11th issues of Circulation Research. This Episode also includes a discussion with Dr Ken Walsh and Dr Ariel Polizio about their study, Experimental TET2 Clonal Hematopoiesis Predisposes to Renal Hypertension Through an Inflammasome-Mediated Mechanism. Article highlights: Ju, et al. NAE1 Crotonylation Regulates Cardiac Hypertrophy Pirri, et al. EPAS1 Atheroprotection via Fatty Acid Metabolism Saleem, et al. Myeloid CD11c+ Cells and JAK2/STAT3/SMAD3 in SSBP Pietsch, et al. Chronic Activation of Tubulin Tyrosination
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38:45
September 2024 Discover CircRes
This month on Episode 64 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the August 30th and September 13th issues of Circulation Research. This Episode also includes a discussion with Drs Stephanie Chung, Ahmed Gharib, and Khalid Abd-Elmoniem from NIDDK about their study, Endothelial Dysfunction in Youth-Onset Diabetes Type 2, A Clinical Translational Study. Article highlights: Zhao, et al. AMPK Phosphorylation of β-Arrestin-1 Blocking β-AR Bashore, et al. Monocytes Profiling and Cardiovascular Disease Chu, et al. Oxysterol-GPR183 Axis and Endothelial Senescence Sigle, et al. Targeting Secreted Cyclophilin A in Failing Hearts
Each 15-minute podcast will provide an overview of the issue’s contents and relevant news in the field of basic/translational cardiovascular biology followed by an in-depth discussion of a featured article. This discussion will pull opinions from the podcast hosts, editorial team, research leaders and authors – both the corresponding authors as well as the trainee(s). We will provide lively discussions that give the listener a behind the scenes look at how science gets done and the implications of these fascinating discoveries.
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