Discover CircRes

This month on Episode 84 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the April 24th and May 8th issue of Circulation Research. This Episode also features a discussion with Dr Mete Civelek and Dr Noah Perry about their study, Female-Biased Vascular Smooth Muscle Cell Gene Regulatory Networks Predict MYH9 as a Key Regulator of Fibrous Plaque Phenotype.
 
Article highlights:
Westhoff, et al. PTEN and PIP3 in AngII-Induced Cardiac Pathology
Witmer, et al. Novel Mode of SCN5A-Mitochondrial Crosstalk
Ghiringhelli, et al. Light-Controllable Humanized Bioengineered Atria
Wang, et al. Exercise-Induced Cardiomyocyte EVs Deliver EPPIR

This month on Episode 83 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the March 27th and April 10th issue of Circulation Research. This Episode also features a discussion with Dr Martin Schwartz and Dr Hanqiang Deng about their study, FOXO1 Integrates Endothelial Hemodynamic, Inflammatory, and Metabolic Pathways in Atherosclerosis.
 
Article highlights:
Tadokoro, et al. CRISPR Base Editing of PKCα Rescues Heart Failure
Joki, et al. PTH Affects Right Heart Hemodynamics
Compendium on Migration of Mitochondria Beyond Cell Boundary

This month on Episode 82 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the February 27th and March 13th issue of Circulation Research. This Episode also features a discussion with Dr John Hall and Dr Ana Omoto from the University of Mississippi Medical Center about their study, Leptin Activates Brain-BAT-Heart Crosstalk to Promote Cardiac Protection.
 
Article highlights:
Sakkers, et al. Atherosclerotic Fibrous Plaques in Women
Ruberto, et al. Mitochondrial Biogenesis and Heart Regeneration
Simon-Chica, et al. Non-Myocytes Modulate Atrial Fibrillation Dynamics
Zhao, et al. USP10 Inhibits cGAS-STING via MTX2

This month on Episode 81 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the January 30th and February 13th issue of Circulation Research. This Episode also features a discussion with Dr Claudia Goettsch and Nicolas Hense, about their study, 1-Phosphatidylinositol 3-Phosphate 5-Kinase Inhibition by Apilimod Promotes an Adipocyte-like Vascular Smooth Muscle Cell Phenotype and Prevents Arterial Calcification.
 
Article highlights:
Hu, et al. CircZBTB44 Inhibits Calcific Aortic Valve Disease
Schemelei, et al. Olfr2 Aggravates AAA Formation
Zhang, et al. Neratinib Protects Against Atherosclerosis
Sun, et al. CD34+ Cells in Transplants

This month on Episode 80 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the January 2nd and January 16th issue of Circulation Research. This Episode also features a discussion with Dr Colin Evans and Dr You-Yang Zhao about their study, The Unexpected Protective Role of Thrombosis in Lung Injury via Endothelial ALOX15.
 
Article highlights:
Viskadourou, et al. Endothelial REST in Atherosclerosis
Torre, et al. Silencing the Chronotropic Heart Rate Response
Chen, et al. Histone Lactylation and Cardiac Hypertrophy
Vázquez-Reyes, et al. Diurnal Neutrophil Function Drives Stroke Outcome