Discover CircRes

This month on Episode 81 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the January 30th and February 13th issue of Circulation Research. This Episode also features a discussion with Dr Claudia Goettsch and Nicolas Hense, about their study, 1-Phosphatidylinositol 3-Phosphate 5-Kinase Inhibition by Apilimod Promotes an Adipocyte-like Vascular Smooth Muscle Cell Phenotype and Prevents Arterial Calcification.
 
Article highlights:
Hu, et al. CircZBTB44 Inhibits Calcific Aortic Valve Disease
Schemelei, et al. Olfr2 Aggravates AAA Formation
Zhang, et al. Neratinib Protects Against Atherosclerosis
Sun, et al. CD34+ Cells in Transplants

This month on Episode 80 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the January 2nd and January 16th issue of Circulation Research. This Episode also features a discussion with Dr Colin Evans and Dr You-Yang Zhao about their study, The Unexpected Protective Role of Thrombosis in Lung Injury via Endothelial ALOX15.
 
Article highlights:
Viskadourou, et al. Endothelial REST in Atherosclerosis
Torre, et al. Silencing the Chronotropic Heart Rate Response
Chen, et al. Histone Lactylation and Cardiac Hypertrophy
Vázquez-Reyes, et al. Diurnal Neutrophil Function Drives Stroke Outcome

This month on Episode 79 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the December 5th issue of Circulation Research. This Episode also features a discussion with Dr Nobuaki Fukuma and Dr Emily Tsai from Columbia University Vagelos College of Physicians and Surgeons about their study, Cardiomyocyte GC1 Mediates Estrogenic Angiogenesis in Right Heart Remodeling.
 
Article highlights:
Hamilton, et al. RyR2 Hyperactivity Remodels Mitochondria
Singhal, et al. TRIB3 Activation Impairs Efferocytosis
Tsai, et al. YAP Induces Glycolysis to Drive Fibroinflammation

This month on Episode 78 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the October 24th and November 7th issues of Circulation Research. This Episode also features a discussion with Thomas Hund and  Drew Nassal from the Ohio State University about their study, The βIV-Spectrin/STAT3 Complex Regulates the Orientation of Cardiac Hypertrophic Growth.
 
Article highlights:
Dhawan, et al. Macrophage DNases Clear Tissue NETs
Pakkiriswami, et al. LV and RV Responses to Elevated Mitochondrial Ca2+
Liu, et al. CCL21 Enhances Platelet Activation
Morales, et al. Vascular Niches and Cardiac Aging