This month on Episode 76 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the August 29th and September 12th issues of Circulation Research. This Episode also features a discussion with Drs Swapnil Sonkusare and Mani Kuppusamy about their manuscript, Paracrine Smooth Muscle-to-Endothelial Signaling via TNF Elevates Blood Pressure in Obesity. Article highlights: Tombor, et al. Immunomodulatory Endothelial Cells After Heart Attack Du, et al. CAR-Ms Engineered In Vivo for Attenuating MIRI Pauza, et al. MC4R Activates Carotid Body in Hypertension Cai, et al. Lkb1 KO in PVAT Drives Aortic Aneurysm Formation
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Discover CircRes August 2025
This month on Episode 75 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the August 1st and August 15th issues of Circulation Research. This Episode also features a discussion with Abigail Ajanel, Dr Robbie Campbell and Dr Frederik Denorme about their study, Mitochondrial Calcium Uniporter Regulates ITAM-Dependent Platelet Activation. Article highlights: Lan, et al. TRIM16 Exacerbates Vascular Calcification Zhang, et al. HADHA Lactylation in Septic Myocardial Depression Li, et al. AR Links to CVMs Baudel, et al. Vascular Panx1 in Diabetic Hyperglycemia
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Discover CircRes July 2025
This month on Episode 74 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the June 20th and July 4th issues of Circulation Research. This Episode also features a discussion with the finalists for the 2025 BCVS Outstanding Early Career Investigator Award. Article highlights: Kimura, et al. Novel Genetic Mouse Model of Aortic Dissection Getaneh, et al. Aspirin Non-Responsiveness in Preeclampsia Introduction to the Compendium on Cardiopulmonary Disease and Exercise: Molecular to Clinical Mechanisms
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Discover CircRes June 2025
This month on Episode 73 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the May 23rd and June 6th issues of Circulation Research. This Episode also includes a discussion with Dr Jae Min Cho and Tzung Hsiai, about their study, Habitual Exercise Modulates Neuroimmune Interaction to Mitigate Aortic Stiffness. Article highlights: Interorgan Crosstalk in Heart Failure and Cardiometabolic Diseases: A Compendium He, et al. NEP in Placental EVs Triggers Hypertension in PE Dennis, et al. FoxO1-zDHHC4-CD36 S-Acylation Axis in Diabetes
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Discover CircRes May 2025
This month on Episode 72 of Discover CircRes, host Cindy St. Hilaire highlights four articles featured in the April 25th and May 9th issues of Circulation Research. This Episode also includes a discussion with Dr Sarah Costantino and Dr Francesco Paneni from University Hospital Zurich about their study, Chromatin Rewiring by SETD2 Drives Lipotoxic Injury in Cardiometabolic HFpEF Article highlights: Laudette, et al. PCSK9 and Mitochondrial Cholesterol in Heart Yang, et al. Srsf3 Limits AS by Lengthening 3′ UTRs of mtARSs Li, et al. CircCDYL Contributes to Cardiac Hypertrophy Zhakeer, et al. Treg Cells Regulate Pulmonary Venous Remodeling
Each 15-minute podcast will provide an overview of the issue’s contents and relevant news in the field of basic/translational cardiovascular biology followed by an in-depth discussion of a featured article. This discussion will pull opinions from the podcast hosts, editorial team, research leaders and authors – both the corresponding authors as well as the trainee(s). We will provide lively discussions that give the listener a behind the scenes look at how science gets done and the implications of these fascinating discoveries.
Brasil