Health & Veritas

Howie and Harlan are joined by Jessica Federer, managing director of the Women's Health Fund and a member of the Yale Institutional Review Board, to discuss how investors can help address the dearth of research on medical problems facing women and why she's optimistic about the future of women's health. Harlan explains how caps on indirect costs affect institutional staffing and research agendas; Howie reports on a lawsuit filed by 26 states against the Trump administration over bureaucratic hurdles to accessing Medicaid coverage.
Show notes: 
Indirect research costs
Yale Research Support: Facilities and Administrative (F&A) Costs
 Yale University: Colleges and Universities Rate Agreement
 "NIH Indirect Costs Policy for Research Grants: Recent Developments"
Jessica Federer
Yale School of Public Health
Megan L. Ranney, Dean of the Yale School of Public Health
Agency for Healthcare Research and Quality
The Women's Health Fund
Yale School of Medicine: Basmah Safdar
Health & Veritas: Basmah Safdar
Women's Health Research at Yale
"Women's Health Research at Yale and SWHR's Symposium Highlights the Power of Collaboration to Advance Women's Health Research"
"CARE for women: Investing in care delivery to improve women's lives and livelihoods"
LinkedIn: Jessica J. Federer
Health & Veritas: Live at the Yale Innovation Summit 2026 
"What Is a General Partner in Venture Capital (VC)?"
"April Koh (Co-Founder & CEO, Spring Health) Featured on Cover of TIME"
"Closing the Gap: How Yale Is Advancing Women's Health Research"
 Medicaid work requirement
"States Sue CMS Over Medicaid Work Requirements Rule, Citing Departure from Earlier Guidance on Medical Frailty"
Massachusetts v. Oz [pp. 208-231] 
Health & Veritas: Ryan Schwarz
 
In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.
Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.
Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Yale School of Public Health biostatistician Bhramar Mukherjee to discuss how statisticians help researchers turn observations into evidence. Harlan examines a new study linking updated COVID vaccination to lower cardiovascular risk and explains why a headline-grabbing result may not settle the question; Howie discusses new Medicaid work requirements and the danger that administrative hurdles could cost vulnerable patients their coverage.
Show notes:
The COVID-19 Vaccine and Cardiovascular Health
"2024-2025 COVID-19 Vaccine and Major Adverse Cardiovascular Events Among US Veterans"
"Target Trial Emulation—A Unifying Approach for Causal Inference From Observational Data | Research, Methods, Statistics"
"Risk Reduction: Absolute vs. Relative Explained"
Bhramar Mukherjee
"Ten Core Concepts for Ensuring Data Equity in Public Health"
Bhramar Mukherjee: "Privacy-enhancing sequential learning under heterogeneous selection bias in multi-site electronic health records data"
Michigan Genomics Initiative
NIH: All of Us Research Program
Megan Ranney, Dean of the Yale School of Public Health
Big Data Summer Immersion at Yale
"The big data paradox and significance"
'What Is Variance in Statistics? Definition, Formula, and Example"
Medicaid work requirements
Center for Health Care Strategies: Summary of Federal Medicaid Work Requirements
"CMS Requires More Restrictive Definition of Medical Frailty in New Medicaid Work
Requirements Rule"
Cleveland Clinic: Frailty
"Coverage losses, substantial confusion in Arkansas following implementation of Medicaid work requirements"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.
Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.
Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Ingrid Katz, director of the Yale Institute for Global Health, to discuss why HIV continues to spread despite the existence of cheap and effective treatment, what AIDS activism can teach us about tackling chronic diseases like hypertension, and what outbreaks like Ebola reveal about the consequences of fragile health systems. Harlan reports on a breach of UK Biobank data and what it means for the future of open science; Howie highlights two recent papers illustrating the importance of vitamin C and the danger of treating it as a cure-all.
Show notes:
The UK Biobank Data Breach
UK Biobank
NIH: All of Us Research Program
"UK Biobank health data listed for sale in China, government confirms"
"UK Biobank: Confidential patient health details still online three months after leaks, BMJ finds"
Ingrid Katz
HIV
PEPFAR
The Global Fund to Fight AIDS, Tuberculosis and Malaria
Differentiated Service Delivery
Hypertension
"Prevalence, Awareness, and Treatment of Hypertension in 37 African Countries: Trends From 2003 to 2022"
Noncommunicable Diseases (NCDs)
Treatment Action Campaign
"Health & Veritas Episode 224: Nicholas Christakis: The Science of Human Connection"
CDC: Ebola Outbreak: Current Situation
South African president Thabo Mbeki
"More than Two Decades Since the Abuja Declaration: A Way Forward for Ending AIDS as a Public Health Threat by 2030"
Vitamin C
Linus Pauling
"High-Dose Intravenous Vitamin C and Mortality and Organ Dysfunction in Severe Burn Injury: The VICTORY Randomized Clinical Trial"
"High-Dose Vitamin C in Burns: Time to Stop"
"A 7-Year-Old Girl with Limping and Leg Pain"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.
Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.
Email Howie and Harlan comments or questions.

Howie and Harlan discuss healthcare headlines including proposed changes to federal research funding, an outbreak of New World screwworm in Texas cattle, and the debate over free expression after researchers were removed from the American Diabetes Association meeting for distributing an editorial critical of federal science policies. They also examine the future of generic GLP-1 drugs, a new Medicare model for heart failure care, and a court ruling with implications for international physicians practicing in the United States.
Show notes:
Research Grants
NIH: NOT-OD-25-132: Supporting Fairness and Originality in NIH Research Applications
Akiko Iwasaki
Health & Veritas Episode 192: Akiko Iwasaki: What Have We Learned About Long COVID?
Stuart Buck
"White House proposes new rules giving political appointees final approval on research grants"
U.S. Constitution: Article II
Skinny Labeling and the Supreme Court
"Supreme Court Upholds Preventive Services Requirement Under ACA"
"Supreme Court Rejects Colorado Law Banning 'Conversion Therapy' for L.G.B.T.Q. Minors"
Hikma Pharmaceuticals USA Inc. v. Amarin Pharma, Inc. (24-889)
"Hikma v. Amarin: Supreme Court Weighs Future of 'Skinny Labeling'"
Value-Based Care
CMS: Value-Based Care
CMS: Hospital Readmission Reduction
New World Screwworm
CDC: New World Screwworm
USDA: New World Screwworm Economic Impact Report
USDA: Eradicating New World Screwworm with Sterile Insect Technique
American Diabetes Association Meeting
"Join the ADA in New Orleans for the 2026 Scientific Sessions"
NIH Director Jay Bhattacharya
Diabetes Care: "Misguided Brushes of a Pen Continue to Dismantle and Destroy Biomedical Research in the United States: We Can No Longer Afford Complacency and Fear. We Must All Act Now!"
"Diabetes researchers ousted from conference after criticizing Trump"
H-1B Visas
Presidential Proclamation on Restriction on Entry of Certain Nonimmigrant Workers
"Federal judge blocks Trump's $100,000 H-1B visa fee"
"Health Care Professionals Sponsored for H-1B Visas in the US"
Exchange Visitors and the J-1 Classification

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.
Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.
Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Mark Siegel, director of Yale's internal medicine residency program, to discuss his approach to mentoring young physicians and building a medical community grounded in purpose and compassion. Harlan examines a breakthrough targeted therapy that could reshape the treatment of pancreatic cancer and other hard-to-treat cancers; Howie tracks the Ebola outbreak in the Democratic Republic of the Congo and argues that policy decisions are hampering the global response.
Show notes:
A Cancer Breakthrough
Pancreatic cancer: Symptoms and causes
"Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer"
"Multi-Selective RAS(ON) Inhibitor Nearly Doubles Survival Time in People With Metastatic Pancreatic Cancer"
"KRAS mutation: from undruggable to druggable in cancer"
Mark Siegel
Mark Siegel: Program Director Notes
Mark Siegel on Substack
Academic medicine
Signaling system
Mark Siegel: "What I've Learned in 63 Years"
Yale School of Medicine: Residency & Fellowship Programs
Mark Siegel: "A Sudden Loss Of Vision" 
Health & Veritas Episode 224: Nicholas Christakis: The Science of Human Connection
Ebola
WHO: Bundibugyo virus disease outbreak, Democratic Republic of the Congo
WHO: Ebola, The Democratic Republic of the Congo, 2026  
WHO: Alert and Response
"'We are catching up'—WHO chief on DR Congo's Ebola fight" 
"Uganda Closes Border With Congo as Ebola Fears Rise"
"Kenyan Court Deals New Blow to Plans for U.S. Ebola Unit"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.
Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.
Email Howie and Harlan comments or questions.