Health & Veritas

• Paul Lombardo: Reckoning with the Dark History of Eugenics

  Howie and Harlan are joined by legal historian Paul Lombardo to discuss his work exploring the role of the legal and medical establishments in eugenics and sterilization in the United States. Harlan reports on his new research on post-vaccination syndrome, a constellation of chronic symptoms experienced by some people after getting the COVID-19 vaccine; Howie discusses the science behind a measles outbreak in Texas. Links: Anxiety in Academia Yale Office of the President: Our commitment to our research mission Post-Vaccination Syndrome Harlan Krumholz: “Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination” “Immune markers of post vaccination syndrome indicate future research directions” Eugenics in America U.S. Supreme Court: Buck v. Bell, 274 U.S. 200 (1927) Paul Lombardo, New England Journal of Medicine: “‘Ridding the Race of His Defective Blood’—Eugenics in the Journal, 1906–1948” “Clarence Thomas tried to link abortion to eugenics. Seven historians told The Post he’s wrong.” Paul Lombardo: Three Generations, No Imbeciles In the Name of Eugenics Paul Lombardo: “Republicans, Democrats, & Doctors: The Lawmakers Who Wrote Sterilization Laws” Measles and Herd Immunity “West Texas measles outbreak grows to 58 cases, including some people who said they were vaccinated” “Supreme Court rejects challenge to Connecticut law that eliminated religious vaccination exemption” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

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• Deborah Rhodes: A Breast-Cancer Screening Breakthrough

  Howie and Harlan are joined by Deborah Rhodes, a Yale internist and the chief quality officer for Yale Medicine and Yale New Haven Health System. They discuss how she helped develop a better approach to scanning for breast cancer in women with dense breast tissue, and the obstacles to wide adoption. Harlan reports on the Trump administration’s plan to slash indirect support for research; Howie explains the potential consequences of cuts to Medicaid. Links: Flu and Research Cuts “Weekly US Influenza Surveillance Report: Key Updates for Week 5, ending February 1, 2025” “This Is One of the Worst Flu Seasons in Decades” “Court Pause on Trump Cuts to Medical Research Funds Is Expanded Nationwide” “What National Institutes of Health funding cuts could mean for U.S. universities” Breast-Cancer Screening TED Talk by Deborah Rhodes: “A test that finds 3x more breast tumors, and why it's not available to you” Deborah Rhodes: “A Survey of Patient Experience During Molecular Breast Imaging” Mayo Clinic Breast Clinic: “How To Decide What To Do If You Have Dense Breasts On Mammogram” Deborah Rhodes: “Dedicated dual-head gamma imaging for breast cancer screening in women with mammographically dense breasts” Cleveland Clinic: Fibroglandular Density Are You Dense? “Evaluation of a Clinical Decision Support System for Imaging Requests” Medicaid “House Republicans release budget plan, with trillions in tax and spending cuts” “Trump's return puts Medicaid on the chopping block” “House GOP releases budget calling for trillions in cuts to taxes and spending” “Red states likely to feel the pain of Medicaid cuts” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

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• The AI in the Doctor’s Office and Other News

  Howie and Harlan discuss a breakthrough pain medication, studies on AI-assisted medicine, the explosion of sports gambling, and the health consequences of the shutdown of USAID.  Links: A First-in-Class Painkiller “F.D.A. Approves Drug to Treat Pain Without Opioid Effects” “FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain” “Peripheral Sodium Channel Blocker Could Revolutionize Treatment for Nerve Pain” “Alabama to Beijing… and Back: The Search for a Pain Gene” AI Screening “Screening performance and characteristics of breast cancer detected in the Mammography Screening with Artificial Intelligence trial (MASAI): a randomised, controlled, parallel-group, non-inferiority, single-blinded, screening accuracy study” “3D mammograms show benefits over 2D imaging, especially for dense breasts”. “The Robot Doctor Will See You Now” USAID and Foreign Aid “Trump and Musk move to dismantle USAID, igniting battle with Democratic lawmakers” “What USAID does, and why Trump and Musk want to get rid of it” “The Status of President Trump’s Pause of Foreign Aid and Implications for PEPFAR and other Global Health Programs” “The Case For Global Health Diplomacy” The Super Bowl and Legalized Sports Gambling “Super Bowl LIX: Betting By The Numbers” “Americans expected to bet $1.39B legally on Super Bowl 2025” “Record 68 million people plan on making Super Bowl bets” “Gambling problems are mushrooming. Panel says we need to act now.” COVID and Flu “The U.S. Is Having Its Mildest Covid Winter Yet” “Estimated Vaccine Effectiveness for Pediatric Patients With Severe Influenza, 2015-2020” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

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  32:59
• Lisa Rosenbaum: Medicine, Well-Being, and Victimhood

  Howie and Harlan are joined by Lisa Rosenbaum, a cardiologist and the national correspondent for the New England Journal of Medicine, to discuss her writing illuminating critical topics in medicine. Harlan reports on the companies claiming to prevent illness through a non-invasive full-body scan; Howie explains the healthcare impact of the Trump administration’s freeze of federal aid.  Links: Body Scanning “Neko Health raises $260M to expand body scan service, fund R&D” Neko Health “Kim Kardashian Promotes $2,500 Body Scan—Here’s What To Know And Why Some Experts Warn Against It”“ “Daniel Ek’s body scanning startup hits £1.4 billion valuation with 100,000 people lining up to pay £299 for a health check” “The rise and fall of Theranos: A timeline” Lisa Rosenbaum Lisa Rosenbaum: “Gray Matters: Analysis and Ambiguity” Lisa Rosenbaum: Not Otherwise Specified podcast Lisa Rosenbaum: “Beyond Moral Injury—Can We Reclaim Agency, Belief, and Joy in Medicine?” Lisa Rosenbaum: “Being Well while Doing Well—Distinguishing Necessary from Unnecessary Discomfort in Training” “The Case Against the Trauma Plot” “The Rise of Therapy-Speak” Lisa Rosenbaum: “On Calling—From Privileged Professionals to Cogs of Capitalism?” “The Moral Crisis of America’s Doctors” The Ezra Klein Show: “Democrats are Losing the War for Attention. Badly.” IMDB: The Doctor The New Administration “Kennedy, Polarizing Pick for Health Secretary, Makes His Senate Debut” “WATCH: Sen. Elizabeth Warren questions RFK Jr. in confirmation hearing” “Trump aid freeze stirs chaos before it is blocked in court” “Trump administration rescinds order attempting to freeze federal aid spending” “Uncertainty Causes Chaos as Trump Threatens Funding Pause for Schools” “Read the Memo Pausing Federal Grants and Loans” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

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  38:23
• Susan Mayne: Keeping Food Safe

  Howie and Harlan are joined by Susan Mayne, a Yale epidemiologist and the former director of the FDA’s Center for Food Safety and Applied Nutrition, to discuss what the agency can and can’t do to keep contaminants out of food and promote healthier eating habits. Harlan reports on the Trump administration’s cancellation of multiple scientific meetings; Howie explains the administration’s health-related executive orders.  Links: Changes at the NIH “Trump administration’s abrupt cancellation of scientific meetings prompts confusion, concern” “The Trump NIH Pick Who Wants to Take On ‘Cancel Culture’ Colleges” Food Safety and the FDA “Beyond Red Dye No. 3: Here’s what parents should know about food colorings” “FDA to Revoke Authorization for the Use of Red No. 3 in Food and Ingested Drugs” U.S. Government Accountability Office: Regulation of Cancer-Causing Food Additives—Time for a Change Nutrition Labeling and Education Act of 1990 FDA: Front-of-Package Nutrition Labeling “Court ruling curbs unfounded claims for memory supplement” FDA: Questions and Answers on Health Claims in Food Labeling FDA Budget Summary FDA: Closer to Zero: Reducing Childhood Exposure to Contaminants from Foods FDA: Food Safety Modernization Act (FSMA) Executive Orders “Breaking Down All of Trump’s Day 1 Presidential Actions” KFF Morning Briefing “Trump orders reflect his promises to roll back transgender protections and end DEI programs” “Trump wants to pull the US out of the World Health Organization again. Here’s what may happen next” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

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