JNIS Podcast

Large language models (LLMs) are moving beyond simple data extraction to complex, guideline-based triage in emergency stroke care. In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, speaks with Dr. Ayman Meddeb, a senior consultant and interventional neuroradiologist at Charité - Universitätsmedizin Berlin, Germany. They discuss his latest paper, "Evaluating accuracy and reasoning capabilities of large language models for acute ischemic stroke management" (https://jnis.bmj.com/content/early/2026/06/23/jnis-2026-025429).

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Evaluating device performance, safety, and procedural efficacy remains essential as mechanical thrombectomy technology for large vessel occlusion (LVO) rapidly evolves. In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, talks with Dr. Marc Ribo, an interventional neurologist at Vall d'Hebron University Hospital in Barcelona, Spain. They discuss his systematic review paper, "Super large bore catheters in the treatment of stroke: systematic review" (https://jnis.bmj.com/content/early/2026/03/27/jnis-2026-025001). 
They discuss published data on super large bore catheters (SLACs; inner diameter ≥0.080 inch), highlighting key metrics including first-pass effect, overall recanalization rates, and navigability through tortuous intracranial vasculature.

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Optimising mechanical thrombectomy speed and efficiency remains a primary focus in acute ischemic stroke management. In this episode, JNIS Editor, Dr. Michael Chen, talks with Dr. Keiko Fukuda, a neurointerventional fellow at UCLA and practising neurointerventionalist in Monterey, California, and Dr. Victor Szeder, Professor of Radiology, Neurology, and Neurosurgery and Director of the Neurointerventional Fellowship at UCLA.

They talk about their multi-centre paper, "Faster reperfusion with combined delivery catheter systems and aspiration first stroke thrombectomy: a multicenter analysis" (https://jnis.bmj.com/content/early/2026/06/19/jnis-2025-024700). The authors discuss data comparing combined delivery catheter systems against standard aspiration setups, highlighting significantly faster times from groin puncture to clot contact and an impressive 67% first-pass effect. They also share key clinical insights on overcoming severe arterial tortuosity.

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Evaluating the 90-day safety and technical feasibility of a percutaneous transvenous approach represents a critical milestone for routing cerebrospinal fluid (CSF) – the clear liquid that cushions the brain and spine – directly into the venous system.

In this episode, JNIS Editor, Dr. Michael Chen, talks with corresponding author Professor Adel Malek (Tufts Medical Center, Boston) (1) to discuss his high-impact paper, "Safety of endovascular shunting for normal pressure hydrocephalus from a prospective, multicenter, single-arm study”.

They discuss the results of this 66-patient, prospective trial, exploring how the novel eShunt system accesses the cerebellopontine angle cistern to drain CSF and relieve pressure. 

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

(1) Neurosurgeon Adel Malek, MD, PhD. Chief of the Cerebrovascular and Endovascular Division in the Department of Neurosurgery, Tufts Medical Center; Professor of Neurosurgery, Tufts University School of Medicine, Boston, USA.

The JNIS Podcast is produced by Letícia Amorim, and is edited by Pritesh Kapadia.

Achieving near-complete reperfusion in medium vessel occlusions (MeVO) is linked to smaller final infarct volumes.  However, this did not translate into a statistically significant shift in 90-day functional independence.  

In this episode,  JNIS Editor-in-Chief, Dr. Michael Chen, and Professor Johanna Ospel (1) discuss the post-hoc analysis of the ESCAPE-MeVO trial, titled "Reperfusion grade and clinical outcome following medium vessel occlusion thrombectomy in the Endovascular Treatment to Improve Outcomes for Medium Vessel Occlusion trial". 

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

(1) Clinical Associate Professor at the University of Calgary and Senior Lecturer at the University of Basel.

The JNIS Podcast is produced by Letícia Amorim, and is edited by Pritesh Kapadia.