Neurocognitive and psychiatric effects after mild COVID-19: meta-analytic evidence
The meta‑analysis discussed in this podcast reveals that adults recovering from COVID‑19 without major medical or psychiatric complications experience mild yet statistically significant cognitive deficits - particularly in processing speed, attention, memory, language, and executive function.
However, as the main author of this paper tells podcast editor and host, Dr Saima Chaudhry, the impairments generally fall below the threshold for clinical concern, with no evidence of profound neuropsychological dysfunction.
Dr Saima Chaudhry is an assistant professor of neurology at the Warren Alpert Medical School, Brown University, Rhode Island, USA.
Dr Stephen Aita is a neuropsychologist in the Department of Neurology at the University of South Alabama, Whiddon College of Medicine, Mobile, Alabama, USA.
Read the paper on the JNNP website: Neurocognitive and psychiatric outcomes associated with postacute covid 19 infection (doi:10.1136/jnnp-2024-333950).
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Vestibular neurology for the generalist
This episode guides the general neurologist through diagnosing and treating dizziness, vertigo, and balance disorders.
Podcast editor and host, Dr Saima Chaudhry, interviews Dr Diego Kaski about his review titled, Vestibular neurology for the generalist. They cover common vestibular conditions, standard assessments, and new advances in genotyping and treatments, allowing a more accessible vestibular neurology.
Dr Saima Chaudhry is an assistant professor of neurology at the Warren Alpert Medical School, Brown University, Rhode Island, USA.
Dr Diego Kaski is a consultant neurologist at the National Hospital for Neurology and Neurosurgery, honorary associate professor at University College London, UK.
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Cyclophosphamide for myasthenia gravis: a comeback?
Patients with refractory or high-risk myasthenia gravis (MG) respond poorly to conventional immunosuppressive therapy, requiring rescue therapies and often experiencing treatment toxicity. The study discussed in this podcast suggests that lower doses of cyclophosphamide can be effective and safe in people with MG, including older age. JNNP's podcast editor, Saima Chaudhry, is joined by Professor Carolina Barnett-Tapia, University of Toronto, University Health Network, who authors the editorial comment 'Cyclophosphamide for myasthenia gravis: a comeback?'(https://jnnp.bmj.com/content/95/12/1095).
The original paper is also free to access: https://jnnp.bmj.com/content/95/12/1096.
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Management methods for acute ischaemic stroke
The effectiveness of endovascular treatment (EVT) in cases of acute ischaemic stroke caused by distal medium vessel occlusion (DMVO) is still unclear. A study in the JNNP assessed the safety and effectiveness of EVT in comparison to the best medical management for DMVO. Podcast host Dr. Saima Chaudhry¹ spoke to some of the paper's authors, Dr. Adam Dmytriw², Dr. Vivek Yedavalli³ and Dr. Hamza Salim³.
Read the paper: Endovascular therapy versus best medical management in distal medium middle cerebral artery acute ischaemic stroke: a multinational multicentre propensity score-matched study
1. Warren Alpert Medical School, Brown University, Rhode Island, USA
2. Neuroendovascular Program, Massachusetts General Hospital, Boston, Massachusetts, USA
3. Radiology, Johns Hopkins Medicine, Baltimore, Maryland, USA
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Distinguishing autoimmune nodopathies from CIDP, with Dr. Ruth Huizinga and Dr. Maarten Titulaer
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) can be difficult to distinguish from autoimmune nodopathy. In this podcast, Dr. Saima Chaudhry (1) is joined from the Netherlands by Dr. Ruth Huizinga (2) and Dr. Maarten Titulaer (3), to discuss their article, "Clinical relevance of distinguishing autoimmune nodopathies from CIDP: longitudinal assessment in a large cohort". They start with explaining what an autoimmune nodopathy really is, patient features to look out for, and the typical testing process for identifying CIDP.
(1) Warren Alpert Medical School, Brown University, Rhode Island, USA
(2) Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
(3) Department of Neurology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Please subscribe to the show on Apple Podcasts, Spotify or find it on your platform of choice. Your feedback and reviews are very appreciated.
Follow JNNP on twitter: @JNNP_BMJ
The Journal of Neurology, Neuroscience and Psychiatry (JNNP) Podcast is proud to reflect JNNP’s ambition to publish the most ground-breaking and cutting-edge research from around the world - jnnp.bmj.com.
Encompassing the entire genre of neurological sciences, our focus is on the common disorders (stroke, multiple sclerosis, Parkinson’s disease, epilepsy, peripheral neuropathy, subarachnoid haemorrhage and neuropsychiatry), but with a keen interest in the Gordian knots that present themselves in the field, such as ALS.
Join Dr. Saima Chaudhry as she hosts in-depth interviews with authors, providing a deeper understanding of their work and shedding new light on their findings. Stay informed with expert discussions and cutting-edge information by subscribing or listening on your favourite podcast platform.
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