Genes and Your Health Series: mRNA: What it is, What it Does, and Hope in Rare Diseases
Host: Denise M. Dupras, M.D., Ph.D.
Guest: Michael Zimmer, Ph.D., Director of Rare Diseases at Moderna Therapeutics
This episode of Genes & Your Health welcomes Dr. Michael Zimmer from Moderna Therapeutics, who discusses how mRNA technology is being applied to treat rare genetic diseases, especially liver-based metabolic disorders. Dr. Zimmer explains how mRNA can help the body produce missing proteins, the challenges of delivering these therapies, and the promise they hold for previously untreatable conditions.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
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38:35
Transplantation Series: Lung Transplantation
Host: Darryl S. Chutka, M.D.
Guest: John Haney, M.D., M.P.H.
Lung transplantation remains a very viable option for patients with end-stage pulmonary disease who no longer respond to medical management. Over 5,000 lung transplants are performed annually around the world. However, its estimated that over 10 times this number are candidates and awaiting a transplant. A shortage of organs remains the major limiting factor. What are the common indications and who’s a candidate for a lung transplant? How are patients prioritized and chosen? What advances have been made in the field and what challenges remain? Finally, what role does the primary care clinician play in lung transplantation? I’ll be discussing these questions and more with my guest, Jack Haney, M.D., M.P.H., chair of cardiothoracic surgery at the Jacksonville campus of the Mayo Clinic. The topic for this podcast is “Lung Transplantation”.
Learn more about this Transplant Series: Mayo Clinic Talks: Donate Life: Transplantation Series | Mayo Clinic School of Continuous Professional Development
Connect with Mayo Clinic’s Transplant Center online at https://mayoclinic.org/transplant or on X @MayoTransplant.
To learn more and register to be an organ donor please visit https://careinfo.mayoclinic.org/organ-donation.
Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development
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29:01
Genes and Your Health Series: Microbiome Wellness Index 2
Host: Denise M. Dupras, M.D., Ph.D.
Guest: Heidi Nelson, M.D., Emeritus Chair of the Department of Surgery and past Chair of the Division of Colon & Rectal Surgery at Mayo Clinic in Rochester
Guest: Jaeyun Sung, Ph.D., Associate Professor of Biomedical Informatics and Senior Associate Consultant II in the Department of Quantitative Health Sciences, Mayo Clinic Rochester
This episode of Genes & Your Health presents the results of the Gut Microbiome Wellness Index 2 study, which examines the differences between the gut microbiomes of healthy and disease-affected populations. Drs. Nelson and Sung discussed a potential future where a stool gut microbiome profile could be used as a barometer of general gut health and outlined how the microbiome can be altered and used to predict overall health. They also covered factors that can contribute to returning the gut microbiome to healthy status after a disruption.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
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46:00
Transplantation Series: What's New in Organ Transplantation Surgery
Host: Darryl S. Chutka, M.D.
Guest: Julie K. Heimbach, M.D.
In 2024, over 48,000 organ transplants were performed in the U.S., representing an increase over the number performed the year before. There was also an increase in the number of transplants performed internationally, offering hope to patients worldwide with organ failure. Significant advancements have been made in the field of organ transplantation, and this is responsible for the success of the organ transplantation program. What are some of the major milestones that have taken place since the initial organ transplant? How has technology improved the success of an organ transplanted? What role will xenotransplantation, or transplantation of animal organs play in the future? These are some of the questions I’ll be asking my guest, Julie K. Heimbach, M.D., transplant surgeon and director of the Transplant Center at the Mayo Clinic. The topic for this podcast is “What’s New in Transplant Surgery?”
Learn more about this Transplant Series: Mayo Clinic Talks: Donate Life: Transplantation Series | Mayo Clinic School of Continuous Professional Development
Connect with Mayo Clinic’s Transplant Center online at https://mayoclinic.org/transplant or on X @MayoTransplant.
To learn more and register to be an organ donor please visit https://careinfo.mayoclinic.org/organ-donation.
Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development
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24:59
Transplantation Series: AI in Transplantation Medicine
Host: Darryl S. Chutka, M.D.
Guest: Rohan M. Goswami, M.D.
The benefits of artificial intelligence or AI are just beginning to be recognized. AI has the potential to improve productivity and efficiency in the workplace, reduce errors and help sort out complex issues. The field of healthcare is finding roles for AI by improving the management of patient data, enhancing clinical decision making and assisting in medical imaging analysis. The integration of AI in transplantation medicine is evolving and has the potential to revolutionize the field. Can AI assist in organ matching and allocation? Can it predict graft survival and organ rejection? What ethical concerns does AI bring to the specialty? I’ll be discussing these issues in this podcast as we tackle the topic of “AI in Transplantation Medicine”. My guest for this podcast is Rohan M. Goswami, M.D., a cardiologist and specialist in Transplant Medicine from the Mayo Clinic.
Learn more about this Transplant Series: Mayo Clinic Talks: Donate Life: Transplantation Series | Mayo Clinic School of Continuous Professional Development
Connect with Mayo Clinic’s Transplant Center online at https://mayoclinic.org/transplant or on X @MayoTransplant.
To learn more and register to be an organ donor please visit https://careinfo.mayoclinic.org/organ-donation.
Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development
Timely consultations relevant for family medicine, primary care, and general internal medicine topics for physicians, nurse practitioners, physician assistants, and residents. Offering CME credit for most episodes at https://ce.mayo.edu/podcast. Produced by @MayoMedEd.