Primary Care Update

This week, Kate, Gary and Mark discuss 3 new studies: whether we can do anything about modifiable risk factors for dementia, whether COVID-19 vaccines are still useful, and how to interpret abnormal shoulder MRIs.

Primary care docs Kate Rowland, Mark Ebell, Henry Barry and Gary Ferenchick talk about 4 new studies: prevention of multimorbidity in people at high risk of diabetes, high-dose vitamin D in healthy older adults, whether screening for skin cancer reduces melanoma mortality, and tirzepatide withdrawal and weight maintenance .

Join primary care professors Mark Ebell, Kate Rowland, Gary Ferenchick and Henry Barry as they discuss 4 new studies: semaglutide for alcohol use disorder, a vibrating cool pack to prevent post vaccination syncope, PCR for 23 respiratory pathogens in primary care to reduce antibiotic use, and fluvoxamine for Long-COVID Fatigue.
Links
Semaglutide for AUD: https://pubmed.ncbi.nlm.nih.gov/42070571/
Vibrating cool pack for vaccine syncope: https://pubmed.ncbi.nlm.nih.gov/41692229/
Point of care PCR for acute RTI: https://pubmed.ncbi.nlm.nih.gov/42149561/
Likelihood that pathogen is commensal vs pathogenic: https://pubmed.ncbi.nlm.nih.gov/39864052/
Fluvoxamine and long COVID: Ann Intern Med. 2026;179(5):621-628  https://pubmed.ncbi.nlm.nih.gov/41911553/

This week primary care physicians Kate Rowland, Mark Ebell, Gary Ferenchick and Henry Barry discuss four new studies: screentime for children, discontinuing levothyroxine, a new mRNA flu vaccine from Moderna, and nicotinamide adenine dinucleotide (NAD) Supplementation for healthy aging.
Links to articles:
AAP screen time policy
Discontinuing levothyroxine study
mRNA flu vaccine from Moderna
NAD supplements
Quiz: Bixomania study

Primary care docs Mark Ebell, Kate Rowland, Henry Barry and Gary Ferenchick tackle 4 new studies: health benefits of cocoa supplements, the best antibiotic for managing uncomplicated UTIs in women, left atrial appendage closure for AF with high bleeding or stroke risk, and evolocumab for primary (sort-of) prevention of MACE in patients with diabetes.
Essential Evidence Plus: www.essentialevidenceplus.com

https://www.iafp.org/2026ac
Cocoa and health: https://pubmed.ncbi.nlm.nih.gov/35294962/
Antibiotics for UTI: https://pubmed.ncbi.nlm.nih.gov/42026010/
Left atrial appendage closure and AF: https://pubmed.ncbi.nlm.nih.gov/41849741/

https://pubmed.ncbi.nlm.nih.gov/41903215/