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The Mind-Gut Conversation Podcast

Emeran Mayer, MD
The Mind-Gut Conversation Podcast
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  • Building Mental Fitness & Healing The Modern Brain with Drew Ramsey, MD | MGC Ep. 103
    Dr. Emeran Mayer sits down with Dr. Drew Ramsey, psychiatrist, author, and pioneer in nutritional psychiatry, for a thought-provoking conversation on how we can proactively strengthen and protect our mental health.Drawing from his new book, Healing the Modern Brain: Nine Tenets to Build Mental Fitness and Revitalize Your Mind, Dr. Ramsey explains what it means to develop “mental fitness” and why small, intentional habits around food, sleep, movement, purpose, and connection can transform how we feel and function in the modern world.Together, they explore the roots of today’s mental health crisis, how modern food and technology are reshaping the brain, and what science reveals about our innate capacity for resilience, growth, and joy.Key Topics Covered:• What “mental fitness” really means and how to build it• The Nine Tenets for strengthening the brain and emotional resilience• How diet and the microbiome influence mood and mental health• Why connection, engagement, and purpose are essential for well-being• How modern stressors from processed food to digital overload impact the brain• Practical steps to rewire your brain and revitalize your mindThis episode is both empowering and deeply practical, reminding us that our brains are not just meant to survive the modern world but to grow, connect, and thrive within it.As always, we invite you to share your thoughts in the comments and subscribe for more episodes exploring the science of mind–body health.Connect with Dr. Mayer:Website: https://www.emeranmayer.comInstagram: https://www.instagram.com/emeranmayer/X: https://www.twitter.com/emeranmayermdFacebook: https://www.facebook.com/EmeranMayerMD/LinkedIn: https://www.linkedin.com/in/emeranmayer/
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  • Healing Trauma and Unlocking Human Potential with Peter Crone | MGC Ep. 102
    Dr. Emeran Mayer welcomes Peter Crone, widely known as The Mind Architect, for a profound conversation on healing trauma, dissolving limiting subconscious beliefs, and unlocking human potential.Peter shares how early life experiences shape the subconscious mind, often creating patterns of fear, anxiety, and self-judgment that hold us back. He explains how shifting awareness and reframing our narratives can open the door to greater freedom, love, and authentic living. Their dialogue bridges Eastern philosophy with modern psychology, offering practical steps to move beyond suffering into resilience and possibility.You’ll also hear how the science of the subconscious intersects with personal transformation, and why cultivating presence can help us break free from being controlled by the past or the future.Key Topics Covered:• Letting go of past and future narratives that shape behavior• The roots of feeling “not good enough” and how to transcend it• Redefining peace as success through radical acceptance• Insights from Eastern philosophy and modern psychology• How trauma imprints the subconscious and shapes behavior• Living with more presence, authenticity, and easeThis episode is both a roadmap and an invitation. By releasing limiting beliefs and healing hidden wounds, we can expand into our fullest human potential.As always, please leave any questions or comments below.We hope you enjoy the episode!This episode is brought to you by Mayer Nutrition. If you are interested in trying Synaptic Bloom, our high-potency Quercetin + supporting polyphenols blend, you can visit mayernutrition.com & use our exclusive podcast discount code MINDGUT for 10% off your first order.Connect with Dr. Mayer:Website: https://www.emeranmayer.comInstagram: https://www.instagram.com/emeranmayerX: https://www.x.com/emeranmayermdFacebook: https://www.facebook.com/EmeranMayerMD/LinkedIn: https://www.linkedin.com/in/emeranmayer/Chapters:00:00 – Introduction01:32 – Peter Crone’s journey and life lessons04:56 – Spirituality, Buddhism, and Eastern influences11:36 – Living in the present and letting go of the past19:13 – Trauma, healing, and the power of choice25:55 – Reprogramming the subconscious mind29:14 – Advertisement: Mayer Nutrition30:51 – Why we feel “not good enough”33:32 – Success, suffering, and hidden drivers of achievement36:41 – Personal reflections and growth37:38 – Psychedelics and altered states of awareness44:27 – The brain as a prediction machine51:26 – Aging, vitality, and redefining time56:14 – Closing thoughts
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  • Menopause, Hormones, and Women’s Health with Dr. Suzanne Gilberg-Lenz | MGC Ep. 101
    Dr. Emeran Mayer welcomes Dr. Suzanne Gilberg-Lenz, physician, author, and women’s health advocate, for an in-depth discussion on menopause, hormone therapy, and the integration of holistic practices into modern medicine.Dr. Gilberg shares her path into women’s health, including the creation of the Menopause Bootcamp to address the lack of education and awareness around menopause. She explains why estrogen plays a vital role in women’s health beyond reproduction and how the Women’s Health Initiative reshaped, and sometimes restricted, perceptions of hormone therapy. The conversation also examines gender bias in medical research, the need for updated guidelines, and the emerging potential of psychedelics in women’s health care.You’ll also hear why community, education, and holistic practices matter so much for empowering women, and how simple lifestyle shifts can improve resilience, wellbeing, and long-term health.Key Topics Covered:• How menopause awareness and conversations are evolving• The significance of estrogen for women’s overall health• The Women’s Health Initiative and its impact on hormone therapy use• How gender bias continues to shape medical research and care• The therapeutic potential of psychedelics in women’s health• Practical holistic practices women can integrate into daily lifeThis conversation highlights the future of women’s health: by blending science, holistic care, and community education, we can better support women through every stage of life.We hope you enjoy!Chapters:00:26 Introduction to Dr. Suzanne Gilberg's Journey06:25 The Shift in Menopause Conversations10:37 Understanding Estrogen and Its Impact15:20 The Women's Health Initiative and Hormone Therapy20:25 Future Directions in Women's Health Research27:00 The Central Role of the Gut29:42 Gender Bias in Medicine34:26 Exploring Psychedelics in Women's Health46:10 Integrating Holistic Practices into Daily Life
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  • How Food Influences Our Mood and Mental Health with Felice Jacka, OAM | MGC Ep. 100
    Dr. Emeran Mayer welcomes Professor Felice Jacka, founder of the Food & Mood Centre and a global leader in nutritional psychiatry, for an in-depth discussion on how diet influences mental health and brain function.Felice shares the groundbreaking research that launched an entire field, from the first studies linking diet quality to depression, to clinical trials demonstrating how dietary changes can improve major depressive disorder. She also takes us beyond the plate, showing how agriculture, soil health, and food systems play a critical role in shaping both human and planetary health.You’ll also hear about her efforts to bring nutritional psychiatry into medical guidelines and education worldwide, and why simple, evidence-based changes, like cutting back on ultra-processed foods and adding more whole grains and legumes, can profoundly affect mood and resilience.Key Topics Covered:• What is nutritional psychiatry and why it matters• How dietary patterns influence depression, anxiety, and cognition• The SMILES and CALM trials: diet as a therapeutic tool• The impact of ultra-processed foods on the microbiome and brain• How soil biodiversity affects nutrient density and mental health• Practical, evidence-based dietary shifts for everyday lifeThis conversation offers both hope and clarity: by improving diet quality, we can not only enhance individual mental health but also address the broader challenges of food systems and planetary well-being.As always, please leave any questions or comments below. We hope you enjoy the episode!Connect with Dr. Mayer:Website: ⁠emeranmayer.com⁠Instagram: ⁠@emeranmayer⁠X: ⁠@EmeranMayerMD⁠YouTube: ⁠Emeran Mayer, MD⁠Chapters:00:00 Introduction to Nutritional Psychiatry05:50 The Complexity of Food and Mental Health11:59 The Impact of Industrial Food Systems18:06 Lifestyle Interventions in Mental Health Treatment30:18 Nutritional Psychiatry Training and Resources38:13 Evidence of Dietary Interventions in Mental Health45:49 Challenges in Changing Dietary Habits57:24 Whole Grains: The Key to Better Health
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  • The Mitochondrial Key to Longevity, Stress, & Holistic Health with Martin Picard, PhD | MGC Ep. 99
    Dr. Emeran Mayer welcomes Martin Picard, PhD, mitochondrial biologist and systems thinker, for a fascinating conversation on the hidden role of mitochondria in health, stress, and consciousness.Martin explains how mitochondria, far beyond being simple “powerhouses of the cell”, are dynamic regulators of energy, emotion, and resilience. He explores their symbiotic relationship with the gut microbiome and how this ancient partnership influences inflammation, mental health, and overall well-being.You’ll also hear about Martin’s concept of “intrinsic health,” a field-like state that integrates biology, energy flow, and human experience. Together, he and Dr. Mayer discuss why understanding energy as the potential for change may reshape how we think about health, stress, and even consciousness itself.Key Topics Covered:• The evolutionary story of mitochondria and their link to the gut microbiome• Why energy is best understood as flow rather than a fixed resource• The impact of stress on mitochondrial health and resilience• How intrinsic health connects science with lived experience• A new paradigm for understanding mental and physical well-beingDiscover how mitochondria and the microbiome together form the foundation of vitality, and why a holistic, systems-based view of health is essential for true well-being. Enjoy!Connect with Dr. Mayer:Website: ⁠emeranmayer.com⁠Instagram: ⁠@emeranmayer⁠Twitter/X: ⁠@EmeranMayerMD⁠YouTube: ⁠Emeran Mayer, MD⁠Episode Chapters:00:00 Introduction to Mitochondria and Microbiome05:26 The Evolutionary Significance of Mitochondria10:35 Energy Dynamics in Biological Systems15:30 Consciousness and Energy: A Philosophical Exploration20:51 The Human Experience and Health22:37 Bridging Biology and Human Experience23:31 Mitochondria and Human Emotions25:28 The Complexity of Mental Health28:58 Intrinsic Health: A New Paradigm36:21 Measuring Intrinsic Health46:10 Stress, Energy, and Health
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The Mind-Gut Conversation brings in experts within various fields of health & science to have a discussion with world-renowned gastroenterologist, neuroscientist and bestselling author of The Mind Gut Connection, Emeran Mayer, MD.
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