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This Week in Parasitism

Vincent Racaniello
This Week in Parasitism
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283 episódios

  • This Week in Parasitism

    TWiP 283: Warming up to cryptosporidiosis

    07/07/2026 | 1h
    TWiP reviews the projected impact of climate change on the burden of Cryptosporidium in Mali, Kenya, and The Gambia.
    Hosts: Vincent Racaniello and Christina Naula
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    Links for this episode
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    Impact of climate change on Cryptosporidium (J Inf Dis)
    Letters read on TWiP 283
    TWiP study – information and survey
    Become a patron of TWiP 
    Send your questions and comments to twip@microbe.tv
    Music by Ronald Jenkees
  • This Week in Parasitism

    TWiP 282: Does he live in New York?

    24/06/2026 | 53min
    TWiP solves the case of the nonbinary patient in his 30s with a history HIV/AIDS presenting with 3 weeks of subjective fevers, chills, generalized weakness and voluminous ostomy output.
    Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula
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    Links for this episode
    Join the MicrobeTV Discord server
    Parasite of the Month: Leucochloridium paradoxum (the green-banded broodsac)
    Letters read on TWiP 282
    TWiP study – information and survey
    New Case

    39-year-old man originally from Guatemala, who moved to one of the NYC boroughs in 2023 and currently lives with his siblings and cousins, presented with headaches. He reports headaches for several months, possibly nearly 1 year. Over the past 2 weeks, he has had intermittent numbness on the left side of his face and in his left arm and foot, with difficulty standing due to sensory changes in his feet. He states these symptoms are new. He reports a fall related to the numbness but denies balance problems. He denies fever or chills. He has intermittent nausea and vomiting but denies diarrhea, abdominal pain, or other complaints. He works as a busboy in a restaurant and states that he only cleans and does not prepare food. In Guatemala, he used to eat street tacos containing pork and beef, sometimes with undercooked meat. He is a former smoker who quit 4 years ago after smoking for 10 years. He drinks alcohol 3–4 times per week, typically 2–4 drinks per occasion, but not daily. He reports no sexual activity for 1–2 years.

    General: no acute distress
    HEENT: NC/AT, anicteric, vEEG
    Neck: supple, normal ROM
    Lungs: clear to auscultation bilaterally 
    Heart: S1, S2 present, normal rate/rhythm
    Abdomen: Soft. Nondistended. Nontender.
    Neuro: AAOx3, no obvious focal deficits
    Extremities: No cyanosis. No edema.\
    Skin: Warm. Dry. No visible rash.
    Psychiatric: Appropriate affect and mood for situation.

    CT HEAD WO IV CONTRAST-Cystic structures scattered along the subarachnoid space, for example, right sylvian fissure/frontotemporal cortical sulci, right > left suprasellar cistern, interpedicular cistern, basal cistern and left sylvian fissure. Associated mass effect with minimal leftward midline shift (0.2-0.3 cm). Calcifications at the left temporal region. There is no obvious acute intracranial hemorrhage.
    Become a patron of TWiP 
    Send your questions and comments to twip@microbe.tv
    Music by Ronald Jenkees
  • This Week in Parasitism

    TWiP 281: Ants under the influence

    22/06/2026 | 58min
    TWiP reviews gene expression in wood ants infected with the larval lancet fluke, which causes them to leave their nest and attach to a flower until they are eaten by a grazing mammal.
    Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula
    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
    Links for this episode
    Join the MicrobeTV Discord server
    Gene expression in wood ants infected with lancet fluke (Mol Ecol)
    Visualisation of the master manipulator in the brain of its ant host (Sci Rep)
    TWiP study – information and survey
    Become a patron of TWiP 
    Send your questions and comments to twip@microbe.tv
    Music by Ronald Jenkees
  • This Week in Parasitism

    TWiP 280: The wriggling diagnosis

    29/05/2026 | 57min
    TWiP solves the case of the 3 yo child, who recently immigrated to the US from Central America, in the ER with acute right lower quadrant abdominal pain and a rather active serpiginous wormlike 'thing' wiggling away in the child's appendix.
    Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula
    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
    Links for this episode
    Join the MicrobeTV Discord server
    Hero: Rudolf Ludwig Carl Virchow (1821-1902)
    Letters read on TWiP 280
    TWiP study – information and survey
    New Case
    3 yo child who recently immigrated to the US from Central America is brought in to the ER with acute right lower quadrant abdominal pain. The mother is concerned about the pain as well as nausea and vomiting. This is acute and the ER provider is concerned that this might be an acute surgical emergency. They order an US in this child and they are surprised to see a rather active serpiginous wormlike 'thing' wiggling away in the child's appendix.  I was sent the Ultrasound video which I really enjoyed. What to do?
    Become a patron of TWiP 
    Send your questions and comments to twip@microbe.tv
    Music by Ronald Jenkees
  • This Week in Parasitism

    TWiP 279: Tolling for hookworms

    01/05/2026 | 50min
    TWiP reviews a phase 2 clinical trial of a recombinant vaccine against N. americanus glutathione S-transferase-1, an enzyme that performs a crucial enzymatic step in
    hookworm blood feeding.
    Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula
    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
    Links for this episode
    Join the MicrobeTV Discord server
    Phase 2 hookworm vaccine clinical trial (Lancet Inf Dis)
    Phase 2 Schistosoma vaccine clinical trial (Vaccines)
    TWiP study – information and survey
    Become a patron of TWiP 
    Send your questions and comments to twip@microbe.tv
    Music by Ronald Jenkees
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Sobre This Week in Parasitism
TWiP is a monthly netcast about eukaryotic parasites. Vincent Racaniello and Dickson Despommier, science Professors from Columbia University, deconstruct parasites, how they cause illness, and how you can prevent infections.
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