LONGEVITY with Nathalie Niddam

Today, I’m joined by Dr. Andrew Salzman, a pioneer in NAD research whose work has spanned everything from pediatric sepsis to cutting-edge longevity science. Dr. Salzman dives deep into why NAD isn’t just another supplement buzzword, but a central molecule powering our energy, resilience, and even fertility.

Wonderfeel is gifting a 7-day Youngr™ supply with every Youngr™ order. Click here and use code NAT at checkout to claim your complimentary gift. Offer ends two weeks from today’s episode.

Episode Timestamps:

Introduction ... 00:00:00

Scientific rigor in supplement development ... 00:06:49

Evolution of medicine and the role of populist health ... 00:09:37

Changing views on aging and longevity ... 00:14:13

NAD’s role in energy, repair, and aging ... 00:17:22

When NAD starts to decline and why it matters ... 00:21:06

Early signs of NAD deficiency ... 00:22:22

NAD’s connection to fertility and reproductive health ... 00:25:03

Gut health, inflammation, and NAD depletion ... 00:34:16

Lifestyle and diet drivers of NAD loss ... 00:39:35

How to assess NAD needs ... 00:42:11

Boosting NAD: supplement strategies and limits ... 00:44:09

NMN versus NR and dosing ... 00:46:05

Wonderfeel’s approach: address depletion and boost levels ... 00:51:53

Commonly reported results and user feedback ... 00:54:52

Creatine’s critical role in cellular energy and aging ... 00:57:55

Future directions: criticism, biomarkers, and personalization ... 01:10:10

Podcast wrap-up, offers, and disclaimer ... 01:15:09

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Dr. Bill Lawrence Episode

Today, I’m joined by the inspiring Dr. Anshul Gupta, a conventionally trained family physician who completely reimagined thyroid care after his own life and health hit a breaking point. Dr. Gupta shares how his battle with fatigue, weight gain, and relentless gut pain led him down a path beyond prescriptions, ultimately transforming his personal health and medical practice. Through functional medicine, he found a way out of his own struggle—and uncovered what so many thyroid patients are missing.
Episode Timestamps:
Welcome and episode introduction ... 00:00:00
Thyroid care gaps and Hashimoto’s paradigm shift ... 00:07:05
Understanding Hashimoto’s and why levothyroxine often falls short ... 00:08:24
Comprehensive thyroid testing and antibody significance ... 00:14:34
Hashimoto’s as an autoimmune gateway and risk escalation ... 00:16:00
The five root causes of Hashimoto’s ... 00:17:15
Chronic infections, spike protein, and immune activation ... 00:21:21
Food’s impact: diet strategy and common dietary pitfalls ... 00:27:01
A three-step framework to reverse Hashimoto’s ... 00:43:44
Practical challenges, especially stress management ... 00:48:00
Peptides and bioregulators: clinical use and observations ... 00:50:09
GLP-1 agonists: thyroid risks and benefits ... 00:58:36
Transformative patient story ... 01:00:48
Thyroid’s centrality to longevity and early testing advice ... 01:03:33
Family support and final resources ... 01:10:09
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Dr. Bill Lawrence Episode

Today, I’m joined by the incredibly insightful Donna Jackson Nakazawa, a science journalist and bestselling author whose work bridges the worlds of neuroscience, storytelling, and personal transformation. Donna has a unique gift for translating complex brain science into real-life strategies—and she’s not afraid to weave in her own powerful journey, from childhood trauma and autoimmune challenges to her fierce quest for hope and healing.
Episode Timestamps:
Podcast introduction and episode overview ... 00:00:00
Chronic stress, childhood adversity, and lifelong health ... 00:07:04
Microglia as the link between stress and brain changes ... 00:10:47
Protector vs destroyer: microglia’s dual role in the brain ... 00:11:21
Neuroplasticity and hope for healing at any age ... 00:15:19
Modern stressors and impacts on kids’ brain health ... 00:17:25
Safety, rumination, and reshaping the brain’s wiring ... 00:18:22
Donna’s personal journey with trauma and autoimmune illness ... 00:38:00
How to break rumination: the MIST framework ... 00:47:40
The science and power of language on health ... 01:01:00
Daily practice tips to disrupt negative thought cycles ... 01:07:26
Rethinking longevity: focus on healthspan and connection ... 01:10:03
How to preorder the book and connect online ... 01:11:38
Podcast outro and disclaimer ... 01:13:02
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Ultimate GI Repair by LVLUP Health — a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 20% off
MassZymes by BiOptimizers – A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat—try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT.
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Dr. Bill Lawrence Episode

Today, I’m joined by Dr. William Davis, a cardiologist-turned-gut detective and bestselling author behind Wheat Belly, Super Gut, and Super Body. In this episode, Dr. Davis breaks down what it really means to have youthful, functional muscle, why maintaining the muscle of your 20s and 30s is about so much more than hitting the gym, and how missing microbes—like L. reuteri—might be the secret to restoring your strength and energy.

Previous Episodes: 

#330: Lose the Bloat, Fix Your GUT: Inside the Microbiome Revolution (Skin, Weight & Longevity Secrets) with Dr William Davis

Episode Timestamps:

Welcome, host and episode introduction ... 00:00:00

What is youthful, functional muscle? ... 00:04:40

Antibiotics, gut microbes, and aging ... 00:07:14

Microbiome’s link to inflammation and mood ... 00:09:31

How gut dysfunction drives disease ... 00:11:07

Conventional medicine’s blind spot and SIBO ... 00:15:26

Testing for SIBO and its prevalence ... 00:21:49

“Microbe-driven” muscle & SIBO yogurt fermentation ... 00:24:17

Why fermented foods and keystone microbes matter ... 00:28:11

GLP-1 obesity drugs: risks and rebound ... 00:31:17

Extreme dieting and lasting metabolic effects ... 00:37:04

From cardiology to gut health: Dr. Davis’s journey ... 00:40:30

DIY approaches for restoring health ... 00:45:05

Modern diet pitfalls vs. ancestral eating ... 00:46:42

L. reuteri, oxytocin, and muscle growth ... 00:53:00

How to start and troubleshoot SIBO yogurt ... 01:01:39

Practical 30-day protocol for vitality ... 01:09:22

Episode wrap-up and thanks ... 01:18:42

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Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level—helping results build over time instead of fading fast. CLICK HERE and use code NAT10.

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Dr. Bill Lawrence Episode

Today, I’m joined by Kyal Van Der Leest, an innovative naturopath, nutritionist, and founder of LVLUP Health, whose formulas are changing the way we think about effective supplementation. Kyal’s journey is deeply personal: from caring for his mother through a long battle with cancer, to overcoming his own intense health struggles with mold illness. These experiences led him to push past superficial fixes and dig deep into what really works for healing and optimizing the body.

Visit www.lvluphealth.com and use code NAT for 20% off

Previous Episodes: 

Episode #116: Does the Perfect Gut Supplement Exist?

Episode #148: Kyal Van Der Leest: Liver Health, Gut Health, and Detoxification

#326: From Brain Fog to Focus: Techniques and Supplements to Enhance Cognitive Function With Kyal Van Der Leest

Episode Timestamps:

Welcome & Podcast intro ... 00:00:00

Pitfalls of cheap supplements & importance of quality ... 00:05:33

Mistakes: symptom chasing, green allopathy, and root causes ... 00:07:38

Blending naturopathy, biochemistry, and biohacking ... 00:10:26

Choosing peptides, herbs, or vitamins for target outcomes ... 00:16:43

Synergy, proprietary blends, and dosing transparency ... 00:18:06

Understanding supplement forms, dosages, and stack simplification ... 00:24:29

Root cause thinking: brain fog, labs, and interconnected symptoms ... 00:34:16

Dopamine, focus, and the risks of overstimulation ... 00:39:59

Peptides in brain health—a step beyond herbs or nutrients ... 00:43:00

Short-term nootropics vs. long-term investments in brain health ... 00:46:17

Longevity levers: muscle, blood sugar, and blood flow ... 00:51:04

Blood sugar regulation—berberine, dihydroberine, and alternatives ... 00:53:32

Liver’s core role in hormones and energy ... 00:55:59

Heart and lung health—peptides, circulation, and overlooked systems ... 01:00:10

Peptides vs. herbs—when to choose and when to avoid ... 01:04:21

Future of peptides, supplement quality, and industry direction ... 01:07:45

Hierarchy: Foundations before biohacks ... 01:08:57

Simple, high-impact upgrade picks & final advice ... 01:11:17

Industry trends, influencer issues, and episode wrap ... 01:17:01

Where to find Kyal and promo code details ... 01:19:19

Our Amazing Sponsors:

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Apollo Neuro — A wearable nervous system support device that uses personalized SmartVibes technology to help you feel calmer, more focused, and better able to shift into rest mode without adding another complicated wellness routine. Head to apolloneuro.com/nat Offer to receive 20% off.

Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level—helping results build over time instead of fading fast. Shop at younggoose.com and use code NAT10.

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Dr. Bill Lawrence Episode