Biosensing offers people real-time insight into their health status. Regular insight, rather than one-time results at an annual checkup, helps people assess how lifestyle factors are impacting their health, whether they need to make adjustments, and which adjustments might have the most impact. Michael Dubrovsky and Josh Clemente discuss the value of biosensing and how it has the potential to disrupt the healthcare industry, shifting from a diagnose-and-treat approach to a preventive and actionable approach. 🎙 What Michael Dubrovsky & Josh Clemente discuss: (5:27) — Why biosensing is important (9:03) — Biosensing is beneficial for turning info into action (14:39) — Annual blood tests are levels from one snapshot in time (24:05) — Measuring a few biomarkers can provide a high amount of data (38:40)— Focusing on prevention is helping to disrupt the US healthcare industry (41:47) — Biosensing can empower people to take control of their health (43:03) — Successfully addressing a health issue involves more than the annual blood draw (46:00) — Biosensing can help elucidate valuable associations (49:58) — Why the future of medicine will focus on the individual (52:14) — Biosensing data from individuals may lead to better solutions for the public (1:07:06) — Biosensing can increase the value of healthcare Transcripts & Show notes Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health. 🔗 Helpful links: Become a Levels member https://levels.link/wnl Watch the conversation: https://youtu.be/zTbxXGisj9M Learn about metabolic health: https://levelshealth.com/blog Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1 📲 Connect: Connect with us on Instagram: https://instagram.com/levels Connect with us on Twitter: https://twitter.com/levels Connect with us on LinkedIn: https://linkedin.com/company/levels-health Connect with us on TikTok: https://tiktok.com/@levelshealth Connect with Michael Dubrovsky on Twitter: https://twitter.com/MikeDubrovsky

We often think that arthritis, musculoskeletal pain, and degenerative joint issues are an inevitable result of aging—but this is far from the truth. Good metabolic health can have significant positive effects on bones, muscles, and joints, and can improve longevity. Conversely, poor metabolic health accelerates the degeneration of joints and tissues for many reasons, like the impact of high uric acid levels, lipid or cholesterol deposits, chronic inflammation, and poor blood flow to tissues. Surgeon Dr. Howard Luks and Levels Co-Founder and Chief Medical Officer Dr. Casey Means discuss musculoskeletal health, how it is related to longevity, how it’s linked to metabolic health, and how to decrease your risks for musculoskeletal pain, degenerative joint issues, and surgery. Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations about metabolic health and how the Levels startup team builds a wellness movement from the ground up in the health and wellness tech industry. 🎙 What Dr. Howard Luks & Dr. Casey Means discuss:  (05:14) - Dr. Casey Means’ personal experience with an orthopedic injury (12:09) - The link between joint and metabolic health (18:19) - Maintaining activity may help improve musculoskeletal health despite osteoarthritic pain (27:53) - Cartilage cells, tendinopathy, and how metabolic health is linked to our tendon health, like with tennis elbow or shoulder pain (37:04) - The importance of blood flow and cellular repair (46:58) - The importance of being your best medical advocate in modern medicine (50:09) - How Dr. Luks started learning about metabolic health and wrote his book, Longevity Simplified (1:02:49) - The simple pillars of longevity (1:24:56) - Why you don't need to be concerned about osteoarthritis (1:32:00) - Trust your body by boosting its regenerative capabilities ⁠Transcripts & Show notes⁠ 🔗 Helpful links: Order "Longevity…Simplified" by Dr. Howard Luks: ⁠https://www.howardluksmd.com/book/ Watch the conversation: ⁠https://youtu.be/XbjORE6D8UA⁠ Become a Levels member: https://levels.link/wnl Learn about metabolic health: ⁠https://levelshealth.com/blog⁠ Find us on YouTube: ⁠https://youtube.com/levelshealth?sub_confirmation=1 📲 CONNECT: Connect with us on Instagram: ⁠https://instagram.com/levels⁠  Connect with us on Twitter: ⁠https://twitter.com/levels⁠  Connect with us on LinkedIn: ⁠https://linkedin.com/company/levels-health⁠  Connect with us on TikTok: ⁠https://tiktok.com/@levelshealth⁠  Connect with Dr. Howard Luks on Instagram: ⁠https://instagram.com/hjluks1⁠  Connect with Dr. Howard Luks on Twitter: ⁠https://twitter.com/hjluks⁠  Connect with Dr. Howard Luks on LinkedIn: ⁠https://linkedin.com/in/howardluksmd⁠  Connect with Dr. Casey Means on Instagram: ⁠https://instagram.com/DrCaseysKitchen⁠  Connect with Dr. Casey Means on Twitter: ⁠https://twitter.com/DrCaseysKitchen⁠  Connect with Dr. Casey Means on LinkedIn: ⁠https://linkedin.com/in/casey-means-md⁠

Fructose and its byproduct uric acid may play a role in the development of Alzheimer’s, thanks to an evolutionary adaptation hijacked by the modern diet. Fructose can be directly consumed, or the body can convert high-glycemic carbohydrates and other foods to fructose. Fructose suppresses some cognitive functions. Dr. Richard Johnson and Dr. Rob Lustig discuss a new study, of which Johnson was an author, on how fructose may be a potential driver in Alzheimer’s, and they hypothesize about fructose’s potential connection to the development of other conditions. 🎙 What Richard Johnson, MD, & Rob Lustig, MD, discuss: (09:50) — Fructose is the driver of some diseases that are on the rise in kids (11:53) — Fructose is a driver of obesity and metabolic syndrome (15:36) — Pharmaceutical treatments for Alzheimer’s disease aren’t as effective as researchers had hoped (17:32)— The research focus of Alzheimer’s is slowly shifting to understanding insulin resistance in the brain (20:41) — Is fructose a root cause of Alzheimer’s? (26:26) — New research suggests fructose induces a foraging response (28:20) — Fructose inhibits areas of the brain to encourage successful foraging (46:48) — We need more research on fructose (1:03:10) —Is fructose a factor in violence? Transcripts & Show notes Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health. 👋 WHO WE ARE: Levels helps you see how food affects your health. With real-time, personalized data gathered through biosensors like continuous glucose monitors (CGM), you learn which diet and lifestyle choices improve your metabolic health so you can live a longer, fuller, healthier life. 🔗 LINKS: Become a Levels member: https://levels.link/wnl Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?: https://www.sciencedirect.com/science/article/abs/pii/S0002916523000047?dgcid=author Learn about metabolic health: https://levelshealth.com/blog Subscribe here on YouTube: https://youtube.com/levelshealth?sub_confirmation=1 📲 CONNECT: Connect with us on Instagram: https://instagram.com/levels Connect with us on Twitter: https://twitter.com/levels Connect with us on LinkedIn: https://linkedin.com/company/levels-health Connect with us on TikTok: https://tiktok.com/@levelshealth Connect with Richard Johnson, MD, on Instagram: https://www.instagram.com/drrichardjjohnson/ Connect with Robert Lustig, MD, on Instagram: https://www.instagram.com/robertlustigmd/

The elevation of uric acid in the body is a causative mechanism in the development of metabolic diseases and contributes to weight gain and fat production. Uric acid is one of the key links between obesity, diabetes, heart disease, neurologic diseases like dementia, ADHD, non-alcoholic fatty liver disease, and more. Dr. David Perlmutter talks with Dr. Casey Means about why we have excess uric acid, what foods cause uric acid production, and what simple steps we can take to lower our uric acid levels to be optimal. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversations about metabolic health and how the Levels startup team builds a wellness movement from the ground up in the health and wellness tech industry. They also cover: How uric acid causes cellular dysfunction and insulin resistance, including oxidative stress, and inflammation, and even prevents insulin from getting out of the bloodstream effectively. Why uric acid would have benefitted us evolutionarily in terms of low access to food and water by letting us more easily pack on weight and raise blood pressure—but how that fights against us today because we now live in an evolutionary-environmental mismatch where this survival mechanism hurts us in the face of caloric abundance. The different dietary and environmental factors that generate uric acid, including fructose, purine-rich foods and umami foods, dehydration, alcohol, and more. How uric acid impairs our hunger signals, drives us to eat, and even promotes risk-taking behavior. How to reverse high uric acid levels as a way to unlock optimal health. 🎙 What Dr. David Perlmutter & Dr. Casey Means discuss: (04:23) - More than just gout (06:17) - A causative role (08:54) - The number one cause of death (16:35) - Evolutionary environmental mismatch (18:08) - High fructose corn syrup (23:39) - The dangers of uric acid (24:49) - Uric acid and dementia (31:44) - Too much fructose (42:43) - Erectile dysfunction and cardiovascular risk (01:04:29) - No need to eat sugar Transcripts & Show notes 🔗 Helpful links: Become a Levels member: https://levels.link/wnl Watch the conversation: https://youtube.com/watch?v=QZ6jPCcFNa8 Learn about metabolic health: https://levelshealth.com/blog Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1 📲 Connect: Connect with us on Instagram: https://instagram.com/levels Connect with us on Twitter: https://twitter.com/levels Connect with us on LinkedIn: https://linkedin.com/company/levels-health Connect with us on TikTok: https://tiktok.com/@levelshealth Connect with Dr. Casey Means on Instagram: https://instagram.com/DrCaseysKitchen Connect with Casey on Twitter: https://instagram.com/DrCaseysKitchen Connect with David Perlmutter, MD on Instagram: https://instagram.com/davidperlmutter Connect with David on Twitter: https://twitter.com/DavidPerlmutter Connect with David on LinkedIn: https://linkedin.com/in/david-perlmutter-md-6a38b930

Receiving a diagnosis of a chronic condition, such as Type 1 diabetes, can be life-changing. A diagnosis is helpful for understanding the cause of symptoms and how to treat, but managing a chronic condition can take a toll on mental health. Tools like a continuous glucose monitor can help empower people and ease the burden of constant care. Jesse Lavine and Ben Grynol discuss the challenges of managing Type 1 diabetes, how Lavine’s diagnosis with Type 1 impacted him, how CGM helped Lavine not only manage the condition but also thrive with it, and how the medical system needs to change to help patients dial in optimal instead of just adequate health. 🎙 What Jesse Lavine & Ben Grynol discuss: (03:39) — A diagnosis of Type 1 diabetes (06:28) — Getting diagnosed with a chronic condition can life-changing (14:18) — Wearing a CGM helped Lavine reduce his insulin intake (26:04) — Having real-time insight into how foods affect your condition and your body (29:47) — Type 1 diabetes does not have to hold you back (35:18) — The current medical system isn’t necessarily set up to empower patients (37:08) — A CGM offers constant feedback that can be used to manage Type 1 diabetes (38:13) — The benefits of having stable blood sugar (41:25)— Managing a chronic condition can lead to medical system burnout (44:59) — Considering the mental health aspects of managing a condition Transcripts & Show notes Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for multiple new shows per week on Levels - Inside the Company, where we have in-depth conversations about how the Levels startup team builds a movement from the ground up in the health and wellness tech industry. 🔗 Helpful links: Become a Levels member: https://levels.link/wnl Learn about metabolic health: https://levelshealth.com/blog Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1 📲 Connect: Connect with us on Instagram: https://instagram.com/levels Connect with us on Twitter: https://twitter.com/levels Connect with us on LinkedIn: https://linkedin.com/company/levels-health Connect with us on TikTok: https://tiktok.com/@levelshealth