Neurology Minute

Dr. Zohaib Siddiqi and Dr. Michel Toledano discuss the diagnosis and management of infectious rhombencephalitis in patients receiving immunomodulatory therapy.
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Trentadue T, Martinez Sosa S, Itoh CY, et al. Clinical Reasoning: A 30-Year-Old Female Patient With Multiple Sclerosis Presenting With Rapidly Progressive Cranial Neuropathies, Weakness, and Ataxia. Neurology. 2025;105(12):e214429. doi:10.1212/WNL.0000000000214429

Dr. Tesha Monteith shares practical tips for improving outcomes for patients with episodic cluster headache.

Dr. Tesha Monteith discusses growing evidence supporting CGRP-targeted therapies as first-line preventive treatment options for people with migraine.
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Reuter U, Dycke AV, Versijpt J, et al. Tolerability, safety, and efficacy of atogepant versus topiramate in adults with migraine (TEMPLE): a randomised, head-to-head, phase 3b trial. Lancet Neurol. 2026;25(9):806-817. doi:10.1016/S1474-4422(26)00214-0

Dr. Casey Kozak discusses why most patients referred with seronegative NMOSD ultimately receive alternative diagnoses, underscoring the challenges of accurate diagnosis in antibody-negative cases. 
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Lang MV, Welk GM, Tajfirouz DA, et al. Unveiling Misdiagnosis: Rethinking Seronegative NMOSD. Mult Scler. 2025;31(11):1381-1384. doi:10.1177/13524585251360648

Dr. Katie Krulisky and Dr. Kelsey Smith discuss the impact of menopause on women with epilepsy, including therapeutics and clinical management during midlife.
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Smith KM, Faubion SS, Vadlamudi L, et al. The Menopause Transition and Epilepsy: A Focus on Therapeutics. Neurol Clin Pract. 2026;16(5):e200650. doi:10.1212/CPJ.0000000000200650