LPS & Endotoxins: The Hidden Toxins Driving Inflammation and "Metabolic Chaos"
In this deep-dive episode, Coach Debbie Potts unpacks one of the most overlooked root causes of chronic inflammation — LPS and endotoxins — and how they quietly sabotage your gut, brain, hormones, and metabolism. LPS (lipopolysaccharides) are fragments of bacteria that normally stay safely inside your gut. But when your gut lining or glycocalyx barrier breaks down — from stress, poor diet, toxins, or sluggish bile flow — these bacterial toxins escape into your bloodstream, triggering a silent firestorm of inflammation known as metabolic endotoxemia. Once in circulation, LPS can: 🧠 Cross into the brain and activate microglia → brain fog, anxiety, and low mood 🔋 Suppress mitochondria → chronic fatigue and poor recovery 💢 Fire up cytokines → joint pain and body aches ⚖️ Disrupt insulin signaling → hormone chaos and weight gain 🔥 Feed back into the gut → worsening leaky gut and inflammation Coach Debbie breaks down: What LPS and endotoxins actually are — and why not all are equally toxic The north-to-south chain reaction from digestion breakdown to systemic inflammation How chronic stress, sluggish bile, and dysbiosis increase your endotoxin load Lab clues to watch (LBP, CD14, Zonulin, hs-CRP, and more) The order of operations to interrupt the cycle: 1️⃣ Reduce LPS generation 2️⃣ Tighten the gut barrier 3️⃣ Restore acid, enzymes, and bile flow 4️⃣ Support detox and lymph drainage 5️⃣ Calm inflammation and rebuild the glycocalyx You'll also hear practical tips for daily gut resilience — like meal hygiene, polyphenol-rich foods, vagus nerve resets, and bile support with phosphatidylcholine, taurine, and bitters. This episode connects the dots between leaky gut, brain fog, and metabolic dysfunction — showing you exactly where to intervene to calm the inflammatory storm and reclaim your energy, focus, and vitality. 🎯 Key takeaway: When endotoxins stay contained, your body thrives. When they leak out, chaos follows. But with the right steps, you can repair, rebuild, and restore your resilience from the inside out. 🔗 Learn more at www.debbiepotts.net ⚠️ Safety Note: Educational only. Partner with a qualified practitioner—especially if you're on medications, have gallbladder disease, significant anemia, active IBD, are pregnant, or have complex conditions.
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