The Itch - How Dupilumab Reduces Mucus Burden in Asthma - VESTIGE Trial
This episode was created in collaboration with, and first posted on, The Itch podcast. Mucus plugging is a challenge in asthma care. It’s thick, sticky mucus that blocks the airways and doesn’t respond to regular inhalers. Even when inflammation improves, these plugs can lower lung function, limit how well medicine works, and make asthma harder to control. In this episode, The Itch breaks down the study: “Effect of Dupilumab on Mucus Burden in Patients with Moderate-to-Severe Asthma,” published Oct. 28, 2025. The analysis looks at whether dupilumab (Dupixent), a biologic that blocks IL-4 and IL-13, can lower mucus burden and improve lung function, especially in people who start with a high “mucus plug score.” Read the paper: https://www.atsjournals.org/doi/abs/10.1164/rccm.202410-1894OC
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ATS Breathe Easy – Controlling COPD with Controller Medication
Chronic Obstructive Pulmonary Disease (COPD) is a group of lung diseases that cause airflow obstruction and other respiratory problems. There are various options for treating COPD, including the highly effective controller medication that helps improve a patient's lung function in the long-term. But as Antonio R. Anzueto, MD, professor of pulmonary and critical care at the University of Texas Health, San Antonio, explains, it is not easy for patients to use these medications. Listen as Dr. Anzueto and host Amy Attaway, MD, Cleveland Clinic, discuss the effectiveness of different COPD treatments, how COPD can affect other organs, and how AI might play into diagnosing COPD as technology advances. Support for this podcast is brought to you by Viatris and Theravance BioPharma.
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ATS Breathe Easy - The Truth Behind Vaping Myths
Vaping and e-cigarettes are often incorrectly thought of as thought of as safe, but research has proven this to be untrue. They are particularly unsafe for the developing brain of children and adolescents. Laura Crotty Alexander, MD, from the University of California, San Diego, explains to host Erika Moseson, MD, MA, that not only does vaping often lead to users moving on to traditional tobacco products, but it also has a major impact on mental health and mood that could be deadly. Check out the ATS Clinical Practice Guideline on treating smoking in adolescents: https://www.atsjournals.org/doi/full/10.1164/rccm.202507-1577ST
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ATS Breathe Easy - The Current State of Procedural Training
Learning how to perform procedures on patients is an important part of medical training, but how do programs decide what to teach? And how do they integrate the latest technology? Host Eddie Qian, MD, from Vanderbilt University Medical Center, talks to Meredith Pugh, MD, MSCI, and Kaele Leonard, MD, of Vanderbilt University Medical Center. Together, they discuss how they think about working with trainees and fellows when it comes to teaching important procedures.
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ATS Breathe Easy - Better Breathing with Anti-inflammatory Rescue Therapies, Part 2
On this episode of the ATS Breathe Easy podcast, host Amy Attaway, MD, of Cleveland Clinic, continues her discussion with asthma expert Njira Lugogo, MD, of University of Michigan. They talk about collaborations in the pulmonary field, the importance of clinical trials, and career advice for those looking to join the field of pulmonology. In case you missed it, check out part one here: https://www.youtube.com/watch?v=4ubMlFuqsVI
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