Freely Filtered, a NephJC Podcast

The Filtrate
Joel Topf kidneyboy.bsky.social
Swapnil Hiremath @hswapnil.medsky.social
Natalie Freidin Program director at Medical University of South Carolina
Sophia Ambruso @sophia_kidney
AC @medpeedskidneys.bsky.social

Special Guests
Carla Nester, Professor of Medicine, Professor of Pediatrics, University of Iowa. Senior author of Valiant

Editing
Natalie Freidin
The Kidney Connection written and performed by Timothy Yau

Show Notes
Trial of Pegcetacoplan in C3 Glomerulopathy and Immune-Complex MPGN NEJM | NephJC

Tubular Secretions
Swapnil: City of Last Chances by Adrian Tchaikovsky (Amazon)
Natalie: Heated Rivalry, the books by Rachel Reid
Carla: Rowing and gold fiber embroidery
AC: Audiobooks, that are appropriate for children: The Giver and Tuck Everlasting
Sophia: Greeking Out podcast and the Wheel of Time by Robert Jordan (Wikipedia)
Joel: This is How You Lose The War by Amal El-Mohtar and Max Gladstone (Amazon)

The Filtrate
Joel Topf kidneyboy.bsky.social
Swapnil Hiremath @hswapnil.medsky.social
Pedro Teixeira @nephcrit.bsky.social

Special Guests
Ewout J. Hoorn, Professor of Medicine Erasmus MC, Netherlands. One of the primary authors.
Harish Seethapathy, Assistant physician at Massachusetts General Hospital

Editing
Vipin Verghese
The Kidney Connection written and performed by Timothy Yau

Show Notes
A Randomized Trial of Targeted Hyponatremia Correction in Hospitalized Patients in NEJM Evidence, in PubMed, in NephJC
Seethapathy: Severe Hyponatremia Correction, Mortality, and Central Pontine Myelinolysis in NEJM Evidence
MacMillan: Osmotic Demyelination Syndrome in Patients Hospitalized with Hyponatremia in NEJM Evidence
SALSA: Risk of Overcorrection in Rapid Intermittent Bolus vs Slow Continuous Infusion Therapies of Hypertonic Saline for Patients With Symptomatic Hyponatremia: The SALSA Randomized Clinical Trial in JAMA Internal Medicine
SALT 1 and 2: Tolvaptan, a Selective Oral Vasopressin V2-Receptor Antagonist, for Hyponatremia in NEJM
Hyponatremia registry: Current treatment practice and outcomes. Report of the hyponatremia registry in Kidney International
The Richard Sterns’ article on the lower mortality with more severe hyponatremia: Mortality and Serum Sodium: Do Patients Die from or with Hyponatremia? in CJASN
The European Hyponatremia Guidelines: Clinical practice guideline on diagnosis and treatment of hyponatraemia in The European Journal of Endocrinology
The American Hyponatremia Guidelines: Diagnosis, Evaluation, and Treatment of Hyponatremia: Expert Panel Recommendations in American Journal of Medicine
Treating hyponatremia: damned if we do and damned if we don't by Tom Berl in Kidney International
Prospective (clamp) versus reactive (rescue) DDAVP in hyponatremia: Safety and efficacy of proactive versus reactive administration of desmopressin in severe symptomatic hyponatremia: a randomized controlled trial in Nature Scientific Reports and as covered in PBFluids
Helbert Rondon’s RCT of urea Urea for Chronic Hyponatremia on ClinicalTrials.gov
Tubular Secretions
Swapnil: Catfishing on CatNet: A Novel by Naomi Kritzer (Amazon)
Harish: Disney Cruise
Edward: Flesh: A Novel (Booker Prize Winner) by David Szalay (Amazon)
Pedro: Scrubs reboot (IMDB)
Joel: KIDNEYcon

The Filtrate
Joel Topf kidneyboy.bsky.social

Special Guests
Dr. Samir Parikh, President of the American Society of Nephrology
Prof. Donal Reddan, President, Irish Nephrology Society
Prof. Catherine Godson
Editing
Joel Topf
The Kidney Connection written and performed by Timothy Yau

Show Notes

Tubular Secretions
Joel Topf, the Dublin Port Greenway Link
Catherine Godson: never heard of the Dublin Port Greenway
Samir Parikh: Trinity College Dublin and specifically the Eavan Boland Library, named after the Irish poet.
Donal Reddan: Something about rugby

The Filtrate
Joel Topf kidneyboy.bsky.social
Pedro Teixeira @nephcrit.bsky.social
Nayan Arora @captainchloride.bsky.social
Anna Gaddy @annagaddy.bsky.social
Swapnil Hiremath @hswapnil.medsky.social and on LinkedIn

Special Guests
Ian McCoy, MD @NephroNinja study author and UCSF
Chi-yuan Hsu Senior author and Chief of the Division of Nephrology at UCSF
Samuel Silver Associate Professor at Queens University in Canada
Editing
Vipin Verghese and Joel Topf

Show Notes
NephJC Discusion: Dialyze Less, Recover More? AKI’s Chance to Get LIBERATE-D
Manuscript: A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney InjuryThe Liberation From Acute Dialysis (LIBERATE-D) Randomized Clinical Trial JAMA | PubMed
Ben’s pilot study: RAD-AKI Pilot study: Recovery After Dialysis-Requiring Acute Kidney Injury (RAD-AKI) (ClinicalTrials.gov)
STARRT-AKI NephJC
Editorial in JAMA: A-E-I-O-U and Sometimes Why—Dialysis in Acute Kidney Injury (JAMA)
What Is Dialytrauma? (Nephrology Times)
How Fragile Are the Results of a Trial? The Fragility Index (PubMedCentral)
Shiffl Trial: Daily Hemodialysis and the Outcome of Acute Renal Failure (NEJM)
AKIKI: Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit (NEJM)
AKIKI2: How Late it was, How Late! (NephJC)
Sam Silver’s study: Promoting Kidney Recovery After Acute Kidney Injury Receiving Dialysis (Recover-AKI) (ClinicalTrial.Gov)
Marie Kondo (Wikipedia)
Tubular Secretions
Swap: The smutty dragon novels of novels of Rebecca Yarros (Wikipedia) Specifically The Empyrean series
Anna: Brisket recipes
Pedro: The Naked Gun (Wikipedia) with Liam Neeson
Ian: ASN Kidney Health Guidance on the Outpatient Management of Patients with Dialysis-Requiring Acute Kidney Injury (PubMed) he really doesn’t get Tubular Secretions.
Nayan: Tilt: A Novel by Emma Pattee (Amazon)
Chi: The Year of Magical Thinking by Joan Didion (Wikipedia) and Innovations in Nephrology (Springer Nature)
Sam: Monopoly Super Electronic Banking Board Game (Amazon)
Joel: Song Sung Blue (Wikipedia)

The Filtrate
Joel Topf (kidneyboy.bsky.social)
AC (@medpeedskidneys.bsky.social)NephMadness
Anna Gaddy (@AnnaGaddy)
Vipin Verghese (@vipvargh.bsky.social)
Natalie Freidin Program director at Medical University of South Carolina
Special Guests
Anna Vinnikova (@kidneywars.bsky.social) Long time game maker for NephMadness and Associate Professor at Virginia Commonwealth University
Autumn Harris Associate Professor of Veterinary Medicine at NC State
Sarah Street MD PhD Assistant Professor of Medicine at Virginia Commonwealth University
Editing
Joel Topf
Show Notes
Animal House scouting report
Autumn Harris on Team Cat
Cheese!