Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

• Dead Mitochondria Might Be Fueling Cardiovascular Aging — Here’s The Fix

  This is a really exciting conversation with Dr. Davide D’Amico from Timeline, where we’re taking a closer look at Urolithin A and heart health. It should come as no surprise that this mitochondrial wonderkin of a nutrient is showing promise here—especially when you consider that 40% of the heart’s weight is mitochondria. That’s an extraordinary factoid, and one that really shifts how we think about aging in the cardiovascular system. What’s particularly compelling in this new preclinical research is that restoring mitochondrial function may do more than just improve ejection fraction. It may also have ripple effects on other hallmarks of aging—like chronic inflammation, cellular stress signaling, and impaired autophagy. I’m thrilled Timeline is continuing to invest in both preclinical and clinical research on this front—and yes, I’m totally nerding out over what they’re up to. ~DrK Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Davide D'Amico, PhD: Director of Discovery and Translational Research at Timeline. With over 15 years of experience in mitochondrial and aging biology, he contributed to developing Urolithin A as a science-backed, clinically validated nutritional product to enhance mitochondrial and muscle health. THANKS TO OUR SPONSOR Timeline: http://Timeline.com/kara10 Email: [email protected] EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Mitopure is making impressive strides for cellular health and longevity. Get 10% off your first order at http://Timeline.com/kara10 with code Kara10. CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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• Why Human-Centered AI Is the Future of Medicine & Mental Wellness

  This episode is a little different from what we usually cover on New Frontiers, but it’s one I couldn’t wait to bring to you. I’ve been thinking a lot about how we—as clinicians—are supposed to keep up in this era of high-throughput technology. We’re swimming in data: labs, multi-omics, diet logs… and an ever-growing stream from wearables. There’s just so much coming at us, and too often, we’re awash in a sea of information without adequate interpretive power. That’s why this conversation with Dr. Rana el Kaliouby felt so important. She’s not just an AI scientist—she’s a visionary and a total badass. She’s building technology that doesn’t just process data, but actually helps us become better clinicians and better humans. We get into the ethics, the potential, the parenting implications—and yes, a personal story about a tragedy in my own hometown that made this all hit very close to home. This one’s powerful, and I hope it sparks the same questions and inspiration for you as it did for me. ~DrKF TRIGGER WARNING This episode touches on sensitive topics, including gun violence and suicide, in the context of empathy, mental health, and technology. If you or someone you know is struggling, please seek help. We share this with care and hope it offers support and perspective. Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Dr. Rana el Kaliouby: http://www.ranaelkaliouby.com Managing Partner, Blue Tulip Ventures: http://www.bluetulip.vc Host, Pioneers of AI Podcast: https://www.pioneersof.ai/ Author of Girl Decoded Dr. Rana el Kaliouby is an Egyptian-American AI scientist, entrepreneur and investor. She is co-founder and Managing Partner of Blue Tulip Ventures, where she invests in startups building Human-Centric AI, and host of the Pioneers of AI podcast. Prior to that, Rana founded her company Affectiva out of MIT, where she pioneered the field of Emotion AI, and successfully exited the company in 2021. She holds a Ph.D. from the University of Cambridge and a Post Doctorate from MIT. THANKS TO OUR SPONSORS DIAMOND Biotics Research: https://www.bioticsresearch.com/ DUTCH: https://dutchtest.com/for-providers GOLD Vibrant Wellness: https://www.vibrant-wellness.com/ TimeLine Nutrition: https://tinyurl.com/bdzx2xms EXCLUSIVE OFFERS FROM OUR SPONSORS OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. https://www.mitoq.com/drkara CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Group Program: https://tinyurl.com/4hvusavw Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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• Legal Pitfalls That Could Destroy Your Practice & How to Avoid Them

  In many ways, the legal side of functional medicine can feel like the Wild West—uncertain, unregulated, and full of risks. The reality is, we all want to have our practices legally buttoned up, but navigating the legal landscape can feel overwhelming—and expensive. What Scott Rattigan, creator of Functional Lawyer, shares in this episode is a real game-changer. He not only breaks down the complexities of the legal side of things but also offers real solutions for us—solutions that can make sure we're covered without the stress and uncertainty that often comes with it. Whether you're just starting out or growing your established practice, you're going to get actionable insights on how to avoid common legal pitfalls, protect your practice, and actually move forward with confidence. It’s a topic that’s been an unmet need for so long, and I'm so excited to bring this to you. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Download 5 Essential Legal Documents for Every Functional or Integrative Medicine Practice: https://www.functionallawyer.com/resource-downloads GUEST DETAILS Scott Rattigan, JD Founder: Functional Lawyer: https://www.functionallawyer.com/kf Co-founder: Origins Incubator - https://www.originsincubator.com/ The Junto Podcast Playlist: https://fxmedlaw.com/junto-youtube LinkedIn: https://www.linkedin.com/in/scott-rattigan/ Email: [email protected] Phone: 941-229-0928 Scott Rattigan, JD, is the founder of Functional Lawyer, offering flat-rate legal solutions to help practitioners protect their licenses and grow their businesses. Inspired by helping his wife build her functional medicine practice, Scott provides high-quality legal support for health coaches, doctors, and more. He’s an attorney, internationally recognized speaker, host of The Junto with Scott Rattigan, bestselling author of The Practice of Telemedicine, and co-founder of the practice success software ReveliaDx. THANKS TO OUR SPONSOR Functional Lawyer: https://www.functionallawyer.com/kf CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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• Why You’re Aging Faster Than You Think & How to Slow It

  I’ve been looking forward to sharing this conversation with you because it’s one I’m truly passionate about. Today, we’re diving into the DunedinPACE epigenetic clock with one of its creators, the brilliant Dan Belsky. It’s a tool I use regularly with my patients, and one that’s transforming how we approach aging and interventions. While this show is a bit more technical than usual, the science is fascinating, and the real-world applications are incredibly valuable. This isn’t just about theory—it’s about practical insights that can change how we measure aging and track the effectiveness of the treatments we offer. Stick with us, and you’ll walk away with actionable knowledge that can make a difference in your practice. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Daniel W Belsky, PhD Website: www.belskylab.com THANKS TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers Biotics Research: https://www.bioticsresearch.com/ GOLD TimeLine Nutrition: https://tinyurl.com/bdzx2xms Vibrant Wellness: https://www.vibrant-wellness.com/ EXCLUSIVE OFFERS FROM OUR SPONSORS OneSkin: Get 15% off OneSkin with the code DRKARA at https://www.oneskin.co/DRKARA Why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. https://www.mitoq.com/drkara CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Group Program: https://tinyurl.com/4hvusavw Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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• What New Research Says About Cartilage Regeneration and Joint Longevity

  What if a human trial of over 1200 patients showed improved mobility and reduced pain in osteoarthritis (OA) patients using a natural combination of boswellia and celery seed extract? What if a second follow-up randomized, placebo-controlled human trial found that within 90 days, this same combination increased OA patients' ability to perform a walk test by over 50%, reduced markers of cartilage degeneration by half and increased markers of cartilage regeneration by half. This is what the research team at Calroy Health Sciences have discovered, putting a tremendous amount of work and financing into studying the effects of the uniquely-developed Cartigenix-HP. Not only that, increased joint space at the end of the trial was clearly visible via radiography, and 90% of the intervention group did not need any "rescue" pharmaceutical medication at the end of the 90 day period (compared with only 20% of the placebo group) and this effect was sustained beyond the end of the trial. I have to say, I am impressed and excited about the potential for this new product to help my patients and I am thinking about other applications like OA prevention and osteoporosis! Listen in to find out more. ~ DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Kiran Krishnan, Microbiologist Kiran Krishnan is a research microbiologist and a health and wellness expert who aims to make complex information understandable to all. He has founded a number of successful health and supplement companies over the last 20 years including co-founding and leading Microbiome Labs, the preeminent, microbiome therapeutics focused brand among healthcare professionals. He is currently a co-founder and partner in 3 other companies that aim to revolutionize wellness care and an advisor to Calroy Health Sciences. He has conducted and published several research studies in scientific journals, has published chapters in scientific textbooks/references books, has global patents and is a sought after speaker on human health and the microbiome. THANKS TO OUR SPONSOR Go to Calroy.com/drkf for exclusive resources and discounts on Cartigenix HP. CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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