JCO Precision Oncology Conversations

In this JCO PO Article Insights episode, host Carolyn Lineen summarizes the article, "Genomics of MTAP Loss in >500,000 Solid Tumor Specimens Profiled Using Comprehensive Genomic Profiling Platforms" by Dean C. Pavlick and colleagues.
LINK TO FULL TRANSCRIPT

JCO PO authors Dr. Matthew Campbell and Dr. Mohammad Moussa at The University of Texas MD Anderson Cancer Center and Baylor College of Medicine, Houston, Texas, share insights into their article, "Efficacy of Immune Checkpoint Blockade in Advanced Upper Tract Urothelial Cancer With DNA Mismatch Repair Deficiency or Microsatellite Instability." Host Dr. Rafeh Naqash and Drs. Campbell and Moussa discuss how the study findings suggest that dMMR/MSI-H may serve as a biomarker of sensitivity to single-agent ICIs in advanced UTUC.
LINK TO FULL TRANSCRIPT

In this JCO PO Article Insights episode, host Jordan Goldstein summarizes the article, "EXONERATE-TRaCE: A Liquid Biopsy for Tracking Response to Anti–Epidermal Growth Factor Receptor–Based Therapy in Metastatic Colorectal Cancer" byTakahashi,  et al.
LINK TO FULL TRANSCRIPT

JCO PO author Dr. Tejas Patil at University of Colorado Cancer Center shares insights into the JCO PO article, "CRESTONE: A Phase II Study of the Efficacy and Safety of the HER3 Monoclonal Antibody, Seribantumab, in Solid Tumors With Neuregulin-1 (NRG1) Fusions". Host Dr. Rafeh Naqash and Dr. Patil discuss the anti-tumor activity and safety data of seribantumab from the CRESTONE study (NCT04383210).
LINK TO FULL TRANSCRIPT

In this JCO PO Article Insights episode, host Carolyn Lineen summarizes the article, "Prognostic Significance of Blood-Based Multicancer Detection in Circulating Tumor DNA: Five-Year Outcomes Analysis" bySwanton et al.
LINK TO FULL TRANSCRIPT