Metabolic Mind

A new study suggests that eating more eggs may be linked to a lower risk of dementia. But what does the research actually show?
Dr. Bret Scher breaks down the headlines, the limitations of observational nutrition research, and the surprisingly important detail hidden in the baseline data.
The people eating the fewest eggs entered the study with what many would consider “healthier” lifestyles:
👉 Lower BMI
👉 More exercise
👉 Less smoking
👉 Higher education levels
Yet they showed worse dementia outcomes than the highest egg consumers.
That doesn’t prove eggs prevent dementia. But it does challenge the long-standing narrative that eggs are harmful, especially when the bias in the study appeared to work against egg consumption from the start.
Dr. Scher also explores:
🥚 Why observational nutrition studies can be misleading
🥚 The concept of “healthy user bias”
🥚 Why dietary cholesterol and heart disease risk are not the same thing
🥚 The nutrient density of eggs, including protein, choline, and healthy fats
🥚 Why the decades-long fear of eggs may not hold up under scrutiny
This conversation is a reminder that nutrition science is often more nuanced than headlines make it seem, and why context matters when interpreting research.
🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.
#MetabolicMind #FoodAsMedicine #NewStudy

Expert Featured:
Dr. Bret Scher
Baszucki Group Medical Director
https://x.com/bschermd

Resources Mentioned:
Egg Intake and the Incidence of Alzheimer’s Disease in the Adventist Health Study-2 Cohort Linked with Medicare Data
https://doi.org/10.1016/j.tjnut.2026.101541

Free CME Clinician Trainings:
Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.
Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-yt

Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.
Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/

About us:
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Fatty liver disease (MASLD) is a major cause of liver disease and even liver failure. But many are surprised to learn it’s not primarily a liver problem. Growing evidence suggests the root issue may be metabolic dysfunction affecting the entire body, and that perspective can drastically change how we approach treating and preventing it.
In this interview, Dr. Bret Scher sits down with Dr. Adam Wolfberg to discuss a newly published study in Hepatology examining how a ketogenic intervention may help prevent metabolic liver disease before it progresses.
The conversation explores MASLD (metabolic dysfunction-associated steatotic liver disease) and MASH (metabolic dysfunction-associated steatohepatitis), conditions that now affect millions of people and are closely linked to obesity, insulin resistance, and type 2 diabetes.
You’ll learn:
Why metabolic diseases are deeply interconnected
How ketogenic interventions may improve liver health
What the new research found about preventing MASLD and MASH
Why weight loss alone may not explain the benefits
How lifestyle interventions compare to pharmaceutical approaches
Why prevention is often overlooked in modern healthcare
The broader connection between metabolic health and chronic disease

Dr. Wolfberg also explains why treating metabolic dysfunction as a whole-body condition, rather than a collection of separate diseases, may change the future of medicine.
🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.
#MetabolicMind #KetogenicTherapy #LiverDisease

Expert Featured:
Dr. Adam Wolfberg
https://www.linkedin.com/in/adamwolfberg/
https://x.com/AdamWolfberg

Resources Mentioned:
https://www.virtahealth.com/
https://www.linkedin.com/company/virta-health/
https://www.instagram.com/virtahealth/

Free CME Clinician Trainings:
Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.
Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-yt

Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.
Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/

About us:
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can insulin resistance increase the risk of suicide?
In this video, Dr. Bret Scher breaks down a new study published in Translational Psychiatry that links metabolic dysfunction with higher rates of suicidal ideation, attempts, and death.
Dr. Scher covers:
How biomarkers like blood glucose, insulin, lipid profiles, and waist circumference relate to suicide risk
How this study fits with the growing evidence connecting metabolism to mental health
How routinely monitoring metabolic markers could impact psychiatric care
How ketogenic and other metabolic therapies could reduce the risk of self-harm

The study adds to a growing body of evidence that mental and metabolic health are deeply connected. While more research is needed, understanding and addressing metabolic dysfunction, like insulin resistance, may be a crucial step in reducing suicide risk and improving psychiatric care

Expert Featured:
Dr. Bret Scher
Baszucki Group Medical Director
https://x.com/bschermd

Resources Mentioned:
Metabolic syndrome increases the risk of suicide attempt: evidence from a population-based cohort and genomic analysis
https://www.nature.com/articles/s41398-025-03575-1

Free CME Clinician Trainings:
Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.
Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-yt

Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.
Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/

About us:
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

For decades, nutrition advice has centered on a single idea: that there’s one “right” way to eat for everyone. The standard low-fat, Mediterranean-style diet approach has shaped how we think about health. But it’s missing a critical piece.
Here, Dr. Bret Scher breaks down the limitations of universal dietary recommendations and why relying on observational nutrition research may not provide clear answers for individual health.
You’ll learn:
Why “evidence-based” nutrition isn’t always as definitive as it seems
The difference between observational studies and causal evidence
Why metabolic health markers like insulin, triglycerides, and body composition matter more than just weight or cholesterol
How different people respond differently to the same diet
When low-carb and ketogenic diets may offer powerful benefits

This discussion challenges the idea of a single “best” diet and instead explores a more personalized approach, one that considers your metabolism, preferences, and long-term sustainability.
As the field evolves, the future of nutrition may lie in moving beyond rigid guidelines and toward individualized care that actually works in the real world.
👉 Explore what a well-formulated ketogenic diet looks like and how it may support metabolic health on our blog: Understanding the Well-Formulated Ketogenic Diet.
🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.
#MetabolicMind #KetogenicTherapy #FoodAsMedicine

Expert Featured:
Dr. Bret Scher
Baszucki Group Medical Director
https://x.com/bschermd

Free CME Clinician Trainings:
Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.
Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-yt

Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.
Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/

About us:
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can ketosis trigger insomnia or even mania? Do you need supplements like L-carnitine to support ketone production? Is whey protein helping or hurting your metabolic health? And how do you maintain or gain weight on a ketogenic diet without losing ketosis?
Harvard-trained psychiatrist Dr. Georgia Ede and cardiologist Dr. Bret Scher tackle your biggest questions in this Metabolic Mailbag episode, breaking down the science behind ketogenic metabolic therapy, including:
Why some people struggle transitioning into ketosis
The role of electrolytes, protein, and meal timing
Brain insulin resistance and mental health
Carnitine deficiency and ketone production
Weight loss vs. weight maintenance on a ketogenic diet
Protein powders, dairy, and whole-food nutrition
Practical ketogenic diet strategies for everyday life

This episode also explores an important theme in metabolic psychiatry: why metabolic health markers often tell us more than standard blood sugar testing alone, and how ketogenic interventions may support brain function even in people without obvious metabolic disease.
Whether you're exploring ketogenic therapy for mental health, improving metabolic health, or simply trying to make keto sustainable long term, this episode is packed with practical insights and nuanced discussion.
🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.
#MetabolicMind #KetogenicTherapy #FoodAsMedicine #Q&A

Expert Featured:
Dr. Bret Scher
https://x.com/bschermd

Dr. Georgia Ede
https://www.diagnosisdiet.com/
https://www.linkedin.com/in/georgiaedemd/
https://www.facebook.com/GeorgiaEdeMd/
https://www.instagram.com/georgiaedemd/?hl=en

Experts Mentioned:
Dr. Guido Frank
https://www.instagram.com/ucsdfranklab/
linkedin.com/in/guido-k-w-frank-b7b42172
https://profiles.ucsd.edu/guido.frank

Resources Mentioned:
https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2026.1749406/full

Free CME Clinician Trainings:
Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.
Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-yt

Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.
Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/

About us:
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.