JAMA Clinical Reviews

Overweight and obesity may cause 10% of new cancer diagnoses annually in the US. In this JAMA Review in the Translational Science series, author Neil Iyengar, MD, of Emory University discusses the biological pathways that may promote cancer in people with overweight or obesity and potential therapies with JAMA Deputy Editor Mary McDermott, MD.

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Obesity and Cancer

Chronic noninfectious diarrhea affects approximately 6% to 7% of adults in the US and significantly impairs quality of life. Author William Chey, MD, of the University of Michigan joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss strategies for diagnosis and treatment of chronic, noninfectious diarrhea.

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Chronic, Noninfectious Diarrhea

Accurate assessment of intravascular volume facilitates decisions about fluid management in patients with volume overload. Author Edmund A. Liles Jr, MD, of the University of Utah joins JAMA Associate Editor David Simel, MD, MHS, to discuss best evidence from physical exam findings including ultrasound, radiographs, and lab studies for determining volume overload in spontaneously breathing patients.

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Does This Patient Have Volume Overload?

Type 1 diabetes affects approximately 2 million people in the US and 8.4 million people worldwide. Author Desmond Schatz, MD, of the University of Florida joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and treatment of type 1 diabetes.

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Type 1 Diabetes

Mark Cuban, entrepreneur, investor, and cofounder of the Mark Cuban Cost Plus Drug Company, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the role of pharmacy benefit managers, insurance formularies, and opaque pricing practices that shape how most Americans access prescription drugs. Hear why he thinks doctors are the good guys in a broken system.

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Pharmaceutical Pricing—JAMA Talks With Mark Cuban