Solutions with Henry Blodget

In the summer of 2024, a baby named KJ was born with a rare disease with a 50% mortality rate. Six months later, he became the first patient to receive personalized gene editing therapy. He is now healthy and thriving. Dr. Jeff Coller, who directs the RNA Innovation Center at Johns Hopkins University, says KJ’s treatment could be the most important medical story of the decade. Today, Dr. Coller explains the ground-breaking science behind KJ’s treatment, and what it will take to bring it mainstream.
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Dr. Kira Hoffman once fought fires as a firefighter. Now she works on starting them - for the sake of wildfire prevention. Dr. Hoffman is a fire ecologist at the University of British Columbia and an expert in why wildfires are getting worse and the solutions that can mitigate their damage. We discuss why she forecasts a “dire” wildfire season this year, how fire policy has transformed over the past century, and what Americans can do across the country to protect their homes now. 
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Recent high-profile tragedies, FAA understaffing and underinvestment, and ballooning TSA lines during the government shutdown have many questioning whether U.S. air travel is as safe as we've been told — but what's the reality? And how do we make it safer, cheaper, and more comfortable?

Darryl Campbell is the aviation-safety correspondent for The Verge. We discuss potentially privatizing the TSA, why we're facing a shortage of air traffic controllers and what we can do about it, and how air travel got needlessly politicized.
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One of the biggest issues in the last few elections has been… immigration. And yet: most Americans support legal immigration and a path to citizenship, and aren't worried about immigrants taking their jobs. So why can't the U.S. enact clear policy?

Alexander Kustov, professor of migration at the University of Notre Dame, recently wrote a book entirely dedicated to this question and practical solutions, titled In Our Interest: How Democracies Can Make Immigration Popular. Today, we discuss his research, his argument that immigration needs to be more selective, and what the U.S. could learn from other countries' immigration policies.
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Ethan Mollick, a Wharton professor and author of the Substack One Useful Thing, describes today’s AI systems as a “jagged frontier," where AI outperforms humans in some tasks but falls short in others. This unevenness means the technology won’t replace all jobs, but it will reshape how we work and which skills matter most. In this episode, we discuss why management and delegation are becoming more valuable, how AI could disrupt the traditional career ladder, and how Mollick is using AI in his classroom to accelerate and deepen learning.
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