Autism (Audio)

UC Davis researcher Christine Nordahl is leading a longitudinal study of children with autism. The Autism Phenome Project looks for early predictors of later outcomes using brain scans and assessments so that early intervention and targeted support can be provided to children diagnosed with autism and co-occurring conditions. Series: "UC Davis News" [Health and Medicine] [Show ID: 41738]

Authentic autism representation begins with listening to autistic people and including them in stories about their lives. Seth Bakke, producer, writer and director of The Rescue, explains how his autistic cousin Aaron and a poem by autistic typer Peter Tran inspired the film. Bakke describes working with Aaron on screen, consulting the Tran family and adapting the set to support his needs. Autistic typers Otto Lana and Peter Tran, joined by Steven Tran, a postdoctoral researcher at UC San Diego, discuss where the film reflects their experiences, where it simplifies communication through typing and why creative freedom must remain grounded in lived experience. They address presuming competence, the difference between hearing and listening, and the need for autistic actors and advisers. Their participation challenges stereotypes and helps audiences see they should be full participants in their own stories. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Arts and Music] [Show ID: 41175]

Human brain organoids help researchers study neurodevelopmental disorders that are difficult to examine directly in developing brain tissue. Giorgia Quadrato, USC, uses cortical organoids derived from human pluripotent stem cells to examine SYNGAP1, an autism risk gene associated in the transcript with intellectual disability, epilepsy, and global developmental delay. Quadrato describes how SYNGAP1 appears in progenitor cells as well as neurons, and how SYNGAP1 haploinsufficiency is linked to disrupted radial glia organization, altered cell division, and faster maturation of cortical projection neurons. She also discusses newer work focused on enteric neurons, gastrointestinal symptoms, and gut motility. By connecting brain development, autism genetics, and the enteric nervous system, this research points to models that may help test therapies and better understand symptoms that affect families. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 41174]

As part of the 2026 Developmental Disabilities Conference, Kavitha Murthi,Assistant Professor, Rutgers University, discusses occupational therapy for autistic people.

Series: "Developmental Disabilities Update" [Health and Medicine] [Show ID: 41463]

Understanding the causes of autism matters for families, public health, and public trust in science. Jonathan Sebat, Ph.D., UC San Diego, explains what research actually shows about the causes of autism and how scientists separate strong evidence from misleading correlations. Sebat examines genetics, de novo mutations, twin studies, developmental regression, and the interplay of genes and environment, helping clarify why autism cannot be reduced to a single trigger. He also addresses why rising diagnoses do not necessarily reflect a simple rise in symptoms and why better research design is essential when studying environmental influences. This work helps explain what science does and does not support and points toward a more rigorous understanding of autism. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Show ID: 41177]