Crohn’s Disease vs. Ulcerative Colitis: High-Yield USMLE Topics You Must Know!
Crohn’s Disease vs. Ulcerative Colitis in USMLE Step 1: these are questions that always come up!Did you know the main difference is in the type of lesion and location? Crohn’s can affect any part of the GI tract, while Ulcerative Colitis is limited to the colon and rectum. 🔑 Tips to ace the exam:• Crohn’s = skip lesions, transmural inflammation, non-caseating granulomas.• UC = continuous lesions, mucosal inflammation, colorectal cancer risk.🔍 Stay tuned for the differences!
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Paroxysmal Nocturnal Hemoglobinuria (PNH): High-Yield USMLE Topics You Must Know!
Paroxysmal Nocturnal Hemoglobinuria (PNH) – YES, it shows up on Step 1, and you need to know the essentials!Here’s what you need to remember:- PIGA gene mutation in hematopoietic stem cells- Deficiency of CD55 and CD59- Complement-mediated intravascular hemolysis- Classic triad: hemolytic anemia, pancytopenia, and venous thrombosis (think Budd-Chiari syndrome)✅ Diagnosis: Flow cytometry✅ Treatment: Eculizumab💡 Exam clue: patient waking up with dark urine in the morning = think PNH!
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Colorectal Cancer: High-Yield USMLE Topics You Must Know!
Understand the presentation, screening, and metastasis pattern — this is a classic Step 1 topic!• Right-sided = bleeds• Left-sided = obstructs• Iron deficiency anemia in older men or postmenopausal women = colorectal cancer until proven otherwise• Colonoscopy is the gold standard• CEA is used for recurrence monitoring, not for screening📲 Follow RD Medicine for more:Instagram: @rdmedicine_orgOfficial Website: www.rdmedicine.com
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Myasthenia Gravis: High-Yield USMLE Topics You Must Know
Myasthenia Gravis is the most common neuromuscular junction disorder, and it’s high-yield for Step 1!Key Features:Fluctuating muscle weakness that worsens with activityPtosis, diplopia, dysphagia, and proximal weaknessMyasthenic crisis → Respiratory failure riskDiagnosis: Ice pack test improves ptosisACh receptor antibodies (highly specific)Chest CT to check for thymomaTreatment:Pyridostigmine (AChE inhibitor)Thymectomy if thymomaImmunotherapy for severe casesMyasthenic crisis → IVIG or plasmapheresisKnow how to differentiate it from Lambert-Eaton syndrome (which improves with use)!
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Measles: High-Yield USMLE Topics You Must Know
Measles is a classic Step 1 topic that you must recognize! In this video, we cover its presentation, complications, and key exam takeaways. What you’ll learn: • 4 C’s of measles: cough, coryza, conjunctivitis & "C"oplik spots • Rash progression: face → downward spread • Dangerous complications: pneumonia, encephalitis, SSPE• Measles vaccine & vitamin A in treatment
Sobre RD Medicine Podcast: Your Guide to a U.S. Medical Career
🎙️ The RD Medicine Podcast is your ultimate guide to building a medical career in the U.S.!
Hosted by Rafael Duarte, MD, Internal Medicine Attending and CEO of RD Medicine, this podcast delivers expert insights on USMLE preparation, clinical rotations, residency applications, and the mindset needed for success.
Whether you're a medical student or an international graduate, you'll find essential strategies to navigate every step of the journey.
📢 Tune in for high-yield discussions, career tips, and everything you need to break barriers and thrive as a physician in the U.S.!
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